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Cat. No.: HY-156646

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Tibremciclib

(Synonyms: BPI-16350)

Tibremciclib is a CDK4 inhibitor with antineoplastic activity.

For research use only. We do not sell to patients.

CAS No.: 2397678-18-9
Formula: C₂₈H₃₂F₂N₈
Molecular Weight:518.60

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Tibremciclib Chemical Structure

CAS No.: 2397678-18-9

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Sample (0.1mg)

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(In Japan)

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

Tibremciclib is a CDK4 inhibitor with antineoplastic activity^[1].

IC₅₀ & Target

CDK4^[1]

All CDK Isoforms :

Chemical Information

CAS No. 2397678-18-9
Molecular Weight 518.60
Formula C₂₈H₃₂F₂N₈
SMILES

C[C@H]1N2C3=CC(C4=NC(NC5=CC=C(C=N5)CN6CCN(CC6)CC)=NC=C4F)=CC(F)=C3N=C2CCC1
Synonyms

BPI-16350
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wang Yiqian, et al. Crystal form of compound useful as CDK4/6 inhibitors for the treatment of cancer. World Intellectual Property Organization, WO2019242719 A1. 2019-12-26.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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