RBM15B - RNA binding motif protein 15B Gene

Homo sapiens

Also known as OTT3; HsOTT3; HUMAGCGB

Gene ID: 29890 | Gene type: protein coding

About RBM15B

Cytogenetic location: 3p21.2 Genomic coordinates (GRCh38): 3:51,391,285-51,397,908 (from NCBI)

This gene has 1 transcript (splice variant), 225 orthologues and 7 paralogues.

Summary

Members of the SPEN (Split-end) family of proteins, including RBM15B, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009]

RBM15B Products(1)

mRNA	Protein	Name
NM_013286.5	NP_037418.3	putative RNA-binding protein 15B

RBM15B Protein Structure

RRM_1

SPOC

0
200
400
600
800
890 a.a.

Protein Preferred Names

Protein Names

putative RNA-binding protein 15B

chromosome 3p21.1 gene sequence

Related Diseases

Diseases

Alias

Wilms Tumor 1

Nephroblastoma	Wilms Tumor
WT1	Wilms' Tumor
Bilateral Wilms Tumor	Wilms Tumor, Type 1
Wilms Tumor, Somatic	Adult Nephroblastoma
Wt1 Disorder	Renal Embryonic Tumor
Adult Kidney Wilms Tumor	Childhood Kidney Wilms Tumor
Nonanaplastic Kidney Wilms Tumor

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11736	RBM15B Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	RBM15B	VGNC	VGNC:45410
Mus musculus	RBM15B	MGD	MGI:1923598
Rattus norvegicus	RBM15B	RGD	RGD:1305937

Name
Email *

	Sorry, but the email address you supplied was invalid.