1. Gene
  2. RPA4 - replication protein A4 Gene

RPA4 - replication protein A4 Gene

Homo sapiens

Also known as HSU24186

Gene ID: 29935 | Gene type: protein coding

About RPA4

Cytogenetic location: Xq21.33 Genomic coordinates (GRCh38): X:96,883,908-96,885,467 (from NCBI)

This gene has 1 transcript (splice variant), 25 orthologues and 2 paralogues.

Summary

This gene encodes a single-stranded DNA-binding protein that is the 30-kDa subunit of the replication protein A complex. Replication protein A is an essential factor for DNA double-strand break repair and cell cycle checkpoint activation. The encoded protein localizes to DNA repair foci and may be involved in the cellular DNA damage response. This protein may also play a role in inhibiting viral replication.[provided by RefSeq, Apr 2010]

RPA4 Products(1)

mRNA Protein Name
NM_013347.4 NP_037479.1 replication protein A 30 kDa subunit

RPA4 Protein Structure

tRNA_anti-codon

tRNA_anti-codon: OB-fold nucleic acid binding domain (74 - 148)

RPA_C

RPA_C: Replication protein A C terminal (165 - 255)

  • 0
  • 100
  • 200
  • 261 a.a.
Protein Preferred Names Protein Names

replication protein A 30 kDa subunit

RF-A protein 4