Kdm5b - lysine demethylase 5B Gene

Also Known as Jarid1b; RGD1565602

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 304809

Summary

Predicted to enable several functions, including histone H3-tri/di/monomethyl-lysine-4 demethylase activity; transcription corepressor activity; and zinc ion binding activity. Involved in cellular response to Fibroblast Growth Factor stimulus; lens fiber cell differentiation; and response to fungicide. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability; breast cancer; and high grade glioma. Orthologous to human KDM5B (lysine demethylase 5B). [provided by Alliance of Genome Resources, Apr 2022]

Kdm5b Products (1)

mRNA Protein Name
NM_001107177.1 NP_001100647.1 lysine-specific demethylase 5B

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to fibroblast growth factor stimulus IEP
IEP: Inferred from expression pattern
24142921 RGD
involved in lens fiber cell differentiation IEP
IEP: Inferred from expression pattern
24142921 RGD
involved in response to fungicide IEP
IEP: Inferred from expression pattern
22496781 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lysine-specific demethylase 5B

  • Jumonji, AT rich interactive domain 1B (RBP2-like)

  • jumonji, AT rich interactive domain 1B (Rbp2 like)

  • lysine (K)-specific demethylase 5B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (22)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-104048 QC6352 Inhibitor 99.13% Unkown
HY-102047B KDOAM-25 citrate Inhibitor 98.56% Unkown
HY-100744 AS8351 Inhibitor 99.88% Unkown
HY-116761 GSK467 Inhibitor 99.34% Unkown
HY-151483 TK-129 Inhibitor ≥98.0% Unkown
HY-100014 KDM5A-IN-1 Inhibitor 99.64% Unkown
HY-119397A KDM5-C49 hydrochloride Inhibitor 98.22% Unkown
HY-101451 PBIT Inhibitor 99.13% Unkown
HY-149091 KDM5B-IN-4 Inhibitor 99.68% Unkown
HY-158432 GT-653 Degrader 99.84% Unkown
HY-100764 YUKA1 Inhibitor 99.15% Unkown
HY-RS07219 KDM5B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-102047 KDOAM-25 Inhibitor / Unkown
HY-128343 KDM4-IN-2 Inhibitor 98.29% Unkown
HY-102047A KDOAM-25 trihydrochloride Inhibitor / Unkown
HY-119397 KDM5-C49 Inhibitor / Unkown
HY-146670 KDM5B-IN-3 Inhibitor / Unkown
HY-158433 KDM5B ligand 2 / Unkown
HY-175036 YTHu78 / Unkown
HY-183618 DW-229 Degrader / Unkown
HY-RS16636 Kdm5b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23071 Kdm5b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kdm5b NCBI NCBI:10765