Cobl - cordon-bleu WH2 repeat protein Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 305497

Summary

Predicted to enable actin monomer binding activity. Predicted to be involved in actin filament organization; collateral sprouting in absence of injury; and positive regulation of cell projection organization. Predicted to act upstream of or within several processes, including chordate embryonic development; liver development; and notochord development. Located in cell cortex and plasma membrane. Orthologous to human COBL (cordon-bleu WH2 repeat protein). [provided by Alliance of Genome Resources, Apr 2022]

Cobl Products (9)

mRNA Protein Name
NM_001401101.1 NP_001388030.1 protein cordon-bleu isoform 1
NM_001401102.1 NP_001388031.1 protein cordon-bleu isoform 2
NM_001401103.1 NP_001388032.1 protein cordon-bleu isoform 3
NM_001401104.1 NP_001388033.1 protein cordon-bleu isoform 4
NM_001401105.1 NP_001388034.1 protein cordon-bleu isoform 5
NM_001401106.1 NP_001388035.1 protein cordon-bleu isoform 6
NM_001401108.1 NP_001388037.1 protein cordon-bleu isoform 7
NM_001401109.1 NP_001388038.1 protein cordon-bleu isoform 8
NM_001401112.1 NP_001388041.1 protein cordon-bleu isoform 10

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21725280 RGD
Cellular Component GO Annotation Evidence References Source
located in cell cortex IDA
IDA: Inferred from direct assay
21725280 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
21725280 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein cordon-bleu

  • cordon-bleu homolog

Cobl Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Cobl D3ZUI5 Pacsin1 Rattus norvegicus Q9Z0W5
IF
21725280
Intra
Cobl D3ZUI5 Pacsin1 Rattus norvegicus Q9Z0W5
Anti Bait CoIP
26334624
Intra
Cobl D3ZUI5 Pacsin1 Rattus norvegicus Q9Z0W5
Anti Bait CoIP
21725280
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02947 COBL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cobl NCBI NCBI:23242