Pbrm1 - polybromo 1 Gene
Also Known as RGD1565549
Species: Rattus norvegicus
Gene Type: protein coding
Gene ID: 306254
Summary
Predicted to enable chromatin binding activity. Involved in positive regulation of dendritic spine development. Predicted to be located in kinetochore and nucleoplasm. Predicted to be part of RSC-type complex. Human ortholog(s) of this gene implicated in extrahepatic bile duct adenocarcinoma; lung non-small cell carcinoma; lung small cell carcinoma; and renal cell carcinoma. Orthologous to human PBRM1 (polybromo 1). [provided by Alliance of Genome Resources, Apr 2022]
Pbrm1 Products (38)
| mRNA | Protein | Name |
|---|---|---|
| XM_039095101.1 | XP_038951029.1 | protein polybromo-1 isoform X1 |
| XM_039095118.1 | XP_038951046.1 | protein polybromo-1 isoform X10 |
| XM_039095106.1 | XP_038951034.1 | protein polybromo-1 isoform X3 |
| XM_039095108.1 | XP_038951036.1 | protein polybromo-1 isoform X4 |
| XM_039095111.1 | XP_038951039.1 | protein polybromo-1 isoform X5 |
| XM_017600287.2 | XP_017455776.1 | protein polybromo-1 isoform X8 |
| XM_039095105.1 | XP_038951033.1 | protein polybromo-1 isoform X2 |
| XM_039095119.1 | XP_038951047.1 | protein polybromo-1 isoform X11 |
| XM_039095113.1 | XP_038951041.1 | protein polybromo-1 isoform X7 |
| XM_039095123.1 | XP_038951051.1 | protein polybromo-1 isoform X15 |
| XM_039095121.1 | XP_038951049.1 | protein polybromo-1 isoform X13 |
| XM_039095120.1 | XP_038951048.1 | protein polybromo-1 isoform X12 |
| XM_039095127.1 | XP_038951055.1 | protein polybromo-1 isoform X18 |
| XM_039095112.1 | XP_038951040.1 | protein polybromo-1 isoform X6 |
| XM_039095117.1 | XP_038951045.1 | protein polybromo-1 isoform X9 |
| XM_017600286.2 | XP_017455775.1 | protein polybromo-1 isoform X8 |
| XM_017600279.2 | XP_017455768.1 | protein polybromo-1 isoform X1 |
| XM_017600281.2 | XP_017455770.1 | protein polybromo-1 isoform X3 |
| XM_039095109.1 | XP_038951037.1 | protein polybromo-1 isoform X4 |
| XM_017600283.2 | XP_017455772.1 | protein polybromo-1 isoform X5 |
| XM_039095128.1 | XP_038951056.1 | protein polybromo-1 isoform X19 |
| XM_039095124.1 | XP_038951052.1 | protein polybromo-1 isoform X16 |
| XM_039095130.1 | XP_038951058.1 | protein polybromo-1 isoform X21 |
| XM_039095133.1 | XP_038951061.1 | protein polybromo-1 isoform X24 |
| XM_039095126.1 | XP_038951054.1 | protein polybromo-1 isoform X17 |
| XM_039095122.1 | XP_038951050.1 | protein polybromo-1 isoform X14 |
| XM_039095129.1 | XP_038951057.1 | protein polybromo-1 isoform X20 |
| XM_039095131.1 | XP_038951059.1 | protein polybromo-1 isoform X22 |
| XM_039095134.1 | XP_038951062.1 | protein polybromo-1 isoform X25 |
| XM_039095132.1 | XP_038951060.1 | protein polybromo-1 isoform X23 |
| XM_039095103.1 | XP_038951031.1 | protein polybromo-1 isoform X1 |
| XM_039095114.1 | XP_038951042.1 | protein polybromo-1 isoform X8 |
| XM_039095116.1 | XP_038951044.1 | protein polybromo-1 isoform X8 |
| XM_039095104.1 | XP_038951032.1 | protein polybromo-1 isoform X1 |
| XM_039095102.1 | XP_038951030.1 | protein polybromo-1 isoform X1 |
| XM_006252686.3 | XP_006252748.1 | protein polybromo-1 isoform X1 |
| XM_039095110.1 | XP_038951038.1 | protein polybromo-1 isoform X4 |
| XM_006252696.3 | XP_006252758.1 | protein polybromo-1 isoform X8 |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in positive regulation of dendritic spine development |
IMP
IMP: Inferred from mutant phenotype
|
31723243 | RGD |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
protein polybromo-1 |
|
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Bioactive Molecules
(20)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-128359 | ACBI1 | 99.92% | Unkown | |
| HY-149026 | GNE-064 | Inhibitor | 99.65% | Unkown |
| HY-151532 | PBRM1-BD2-IN-5 | Inhibitor | 99.75% | Unkown |
| HY-150289 | GNE-235 | 98.86% | Unkown | |
| HY-151538 | PBRM1-BD2-IN-8 | Inhibitor | 98.05% | Unkown |
| HY-151529 | PBRM1-BD2-IN-2 | Inhibitor | 99.0% | Unkown |
| HY-148381 | A947 | / | Unkown | |
| HY-151528 | PBRM1-BD2-IN-1 | Inhibitor | / | Unkown |
| HY-151530 | PBRM1-BD2-IN-3 | Inhibitor | / | Unkown |
| HY-151531 | PBRM1-BD2-IN-4 | Inhibitor | / | Unkown |
| HY-151533 | PBRM1-BD2-IN-6 | Inhibitor | / | Unkown |
| HY-151534 | PBRM1-BD2-IN-7 | Inhibitor | / | Unkown |
| HY-161881 | SMARCA2-IN-9 | Inhibitor | / | Unkown |
| HY-171774 | PBRM1/SMARCA2,4-ligand-1 | / | Unkown | |
| HY-174237 | PBRM1/SMARCA2,4 binder-1 | / | Unkown | |
| HY-175756 | SMARCA2/4 degrader-1 | Degrader | / | Unkown |
| HY-183007 | LJM133 | Degrader | / | Unkown |
| HY-RS10105 | PBRM1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS17918 | Pbrm1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS24387 | Pbrm1 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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