RAB37 - RAB37, member RAS oncogene family Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 326624

About RAB37

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:74,671,131-74,747,335 (from NCBI)

This gene has 16 transcripts (splice variants), 168 orthologues and 68 paralogues. Broad expression in spleen (RPKM 9.4), bone marrow (RPKM 7.1) and 20 other tissues.

Summary

Rab proteins are low molecular mass GTPases that are critical regulators of vesicle trafficking. For additional background information on Rab proteins, see MIM 179508.[supplied by OMIM, Apr 2006]

RAB37 Products (5)

mRNA Protein Name
NM_001006638.3 NP_001006639.1 ras-related protein Rab-37 isoform 2
NM_001163989.3 NP_001157461.2 ras-related protein Rab-37 isoform 4
NM_001163990.2 NP_001157462.1 ras-related protein Rab-37 isoform 5
NM_001330471.2 NP_001317400.1 ras-related protein Rab-37 isoform 6
NM_175738.5 NP_783865.1 ras-related protein Rab-37 isoform 3

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum-Golgi intermediate compartment IDA
IDA: Inferred from direct assay
15308636 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RAB37 Protein Structure

Ras

Ras: Ras family (31 - 191)

  • 0
  • 100
  • 200
  • 223 a.a.
Protein Preferred Names Protein Names

ras-related protein Rab-37

  • RAB37, member of RAS oncogene family

RAB37 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RAB37 Q96AX2 MAL2 Homo sapiens Q969L2
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Prostate Transitional Cell Carcinoma

  • Transitional Cell Carcinoma Of Prostate

  • Primary Prostate Urothelial Carcinoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11551 RAB37 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21713 Rab37 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28231 Rab37 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus RAB37 MGD MGI:1929945
Rattus norvegicus RAB37 RGD RGD:2319982
Canis familiaris RAB37 VGNC VGNC:45279
Macaca mulatta RAB37 VGNC VGNC:81535
Bos taurus RAB37 VGNC VGNC:33645
Felis catus RAB37 VGNC VGNC:97589
Others RAB37 NCBI