RAB41 - RAB41, member RAS oncogene family Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 347517

About RAB41

This gene has 3 transcripts (splice variants), 69 orthologues and 68 paralogues. Low expression observed in reference dataset.

Summary

This gene encodes a small GTP-binding protein that belongs to the largest family within the Ras superfamily. These proteins function as regulators of membrane trafficking. They cycle between inactive GDP-bound and activated GTP-bound states, which is controlled by GTP hydrolysis-activating proteins (GAPs). This family member can be activated by the GAP protein RN-Tre, and it is localized to the Golgi complex. [provided by RefSeq, May 2010]

RAB41 Products (2)

mRNA Protein Name
NM_001032726.3 NP_001027898.2 ras-related protein Rab-41 isoform 1
NM_001363807.1 NP_001350736.1 ras-related protein Rab-41 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RAB41 Protein Structure

Ras

Ras: Ras family (33 - 192)

  • 0
  • 100
  • 200
  • 222 a.a.
Protein Preferred Names Protein Names

ras-related protein Rab-41

  • RAB41, member RAS homolog family

RAB41 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RAB41 Q5JT25 REL Homo sapiens Q04864
Y2H Prey Pooling
25416956
Intra
RAB41 Q5JT25 REL Homo sapiens Q04864
Y2H Array
25416956
Intra
RAB41 Q5JT25 TCF4 Homo sapiens P15884
Y2H Prey Pooling
25416956
Intra
RAB41 Q5JT25 TCF4 Homo sapiens P15884
Validated Y2H
25416956
Intra
RAB41 Q5JT25 PPP5C Homo sapiens P53041
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Microvillus Inclusion Disease

  • Congenital Microvillous Atrophy

  • Intractable Diarrhea Of Infancy

  • Congenital Familial Protracted Diarrhea With Enterocyte Brush-Border Abnormalities

  • Davidson Disease

  • Microvillous Inclusion Disease

  • Congenital Microvillus Atrophy

  • Mvid

  • Diarrhea 2 With Microvillus Atrophy

  • Mvd

  • Congenital Familial Protracted Diarrhea

  • Davidson'S Disease

  • Familial Enteropathy, Microvillus

  • Microvillus Atrophy, Congenital

  • Congenital Enteropathy

  • Familial Protracted Enteropathy

  • Microvillous Atrophy

  • Microvillus Atrophy With Diarrhea 2

  • Idi
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11565 RAB41 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11567 RAB43 Human Pre-designed siRNA Set A Pre-designed Set / Unkown