RILPL1 - Rab interacting lysosomal protein like 1 Gene

Also Known as RLP1; OPDM4; GOSPEL

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 353116

About RILPL1

Cytogenetic location: 12q24.31 Genomic coordinates (GRCh38): 12:123,470,054-123,533,719 (from NCBI)

This gene has 5 transcripts (splice variants), 258 orthologues, 4 paralogues and is associated with 1 phenotype. Broad expression in heart (RPKM 11.5), thyroid (RPKM 5.2) and 23 other tissues.

Summary

Predicted to enable protein dimerization activity. Predicted to be involved in several processes, including cilium assembly; epithelial cell morphogenesis; and protein transport from ciliary membrane to plasma membrane. Located in cytosol; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

RILPL1 Products (4)

mRNA Protein Name
NM_001319243.2 NP_001306172.1 RILP-like protein 1 isoform 2
NM_001319244.2 NP_001306173.1 RILP-like protein 1 isoform 3
NM_001319302.2 NP_001306231.1 RILP-like protein 1 isoform 3
NM_178314.5 NP_847884.2 RILP-like protein 1 isoform 1

RILPL1 Protein Structure

Jnk-SapK_ap_N

Jnk-SapK_ap_N: JNK_SAPK-associated protein-1 (27 - 176)

RILP

RILP: Rab interacting lysosomal protein (295 - 354)

  • 0
  • 100
  • 200
  • 300
  • 403 a.a.
Protein Preferred Names Protein Names

RILP-like protein 1

  • GAPDH competitor of SIAH protein enhances life

RILPL1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RILPL1 Q5EBL4 RAB8A Homo sapiens P61006
Anti Tag CoIP
29125462
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Oculopharyngodistal Myopathy 4

  • OPDM4
Alstrom Syndrome

  • ALMS

  • Alström Syndrome

  • Alss

  • Alstrom-Hallgren Syndrome

  • Alstroem Syndrome
Parkinson Disease, Late-Onset

  • Parkinson Disease

  • Parkinson'S Disease

  • PD

  • PARK

  • Parkinson Disease, Susceptibility To

  • Late Onset Parkinson'S Disease

  • Late Onset Parkinson Disease

  • Paralysis Agitans

  • Primary Parkinsonism

  • Idiopathic Parkinson Disease

  • Parkinson'S

  • Parkinson Disease, Late-Onset, Susceptibility To

  • Parkinson Disease, Age Of Onset, Modifier

  • Lewy Body Parkinson Disease

  • Idiopathic Parkinson'S Disease

  • Pd - [Parkinson Disease]

  • Parkinson Disease Nos

  • Parkinson, Nos

  • Primary Parkinson Disease
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11974 RILPL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta RILPL1 VGNC VGNC:76842
Felis catus RILPL1 VGNC VGNC:64628
Mus musculus RILPL1 MGD MGI:1922945
Rattus norvegicus RILPL1 RGD RGD:1307973
Bos taurus RILPL1 VGNC VGNC:33967
Canis familiaris RILPL1 VGNC VGNC:45577
Others RILPL1 NCBI