IL9 - interleukin 9 Gene
Also Known as P40; HP40; IL-9
Species: Homo sapiens
About IL9
This gene has 1 transcript (splice variant) and 94 orthologues. Low expression observed in reference dataset.
Summary
The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents Apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq, Jul 2008]
IL9 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_000590.2 | NP_000581.1 | interleukin-9 precursor |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables cytokine activity |
IDA
IDA: Inferred from direct assay
|
24487305 | GOA |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in interleukin-9-mediated signaling pathway |
IDA
IDA: Inferred from direct assay
|
24487305 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| is active in extracellular space |
IDA
IDA: Inferred from direct assay
|
33463482 | GOA |
IL9 Protein Structure
IL7: Interleukin 7/9 family (15 - 142)
- 0
- 100
- 144 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
interleukin-9 |
|
Recombinant IL9 Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P7046 | IL-9 Protein, Human (CHO) | P15248 (Q19-I144) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P70539 | IL-9 Protein, Human (HEK293, His) | P15248 (Q19-I144) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P73228 | IL-9 Protein, Human (sf9, His) | P15248/NP_000581.1 (Q19-I144) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P700134AF | Animal-Free IL-9 Protein, Human (His) | P15248 (Q19-I144) | ≥ 95%, as determined by reducing SDS-PAGE. |
IL9 Antibodies
| Cat. No. | Product Name | Application | Reactivity |
|---|---|---|---|
| HY-P811287 | IL-9 Antibody | WB, IHC-P | Human, Mouse, Rat |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Severe Combined Immunodeficiency, X-Linked |
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| Trichuriasis |
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| Allergic Disease |
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| Allergic Asthma |
|
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| Asthma |
|
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| Severe Combined Immunodeficiency |
|
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| Posterior Uveitis |
|
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| Bronchitis |
|
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| Rhinitis |
|
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| Allergic Rhinitis |
|
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| Myelitis |
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| Tetanus |
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| Combined Immunodeficiency |
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| Schistosomiasis |
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| Trichinosis |
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| Bronchiolitis |
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| Hypereosinophilic Syndrome |
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| Trypanosomiasis |
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| Uveitis |
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| Chronic Asthma |
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| Lung Disease |
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| Lymphoma, Hodgkin, Classic |
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| Parasitic Helminthiasis Infectious Disease |
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| Respiratory Allergy |
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| Autoimmune Disease |
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| Bronchial Disease |
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| Nasal Cavity Disease |
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| Malaria |
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| Legume Allergy |
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| Nose Disease |
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| Ascaris Lumbricoides Infection |
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| Fruit Allergy |
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| Sarcoidosis 1 |
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| Peanut Allergy |
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| Intrinsic Asthma |
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| Acute Asthma |
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| Filarial Elephantiasis |
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| Multiple Sclerosis |
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| Contact Dermatitis |
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| Food Allergy |
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| Interstitial Lung Disease 2 |
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| Cystic Fibrosis |
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| Pulmonary Disease, Chronic Obstructive |
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| Allergic Contact Dermatitis |
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| Dermatitis, Atopic |
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| Esophagitis, Eosinophilic, 1 |
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| Common Cold |
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| T-Cell Acute Lymphoblastic Leukemia |
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| Bronchiectasis 2 |
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| Lymphoma, Non-Hodgkin, Familial |
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| Ciliary Dyskinesia, Primary, 5 |
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| Cerebral Palsy |
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| Celiac Disease 1 |
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| Skin Disease |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Macaca mulatta | IL9 | VGNC | VGNC:73736 |
| Mus musculus | IL9 | MGD | MGI:96563 |
| Felis catus | IL9 | VGNC | VGNC:67786 |
| Rattus norvegicus | IL9 | RGD | RGD:620049 |
| Bos taurus | IL9 | VGNC | VGNC:30171 |
| Others | IL9 | NCBI |