BAG5 - Bag5 BAG cochaperone 5 Gene

Also Known as Bag5l1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 366734

Summary

Enables chaperone binding activity and ubiquitin protein Ligase binding activity. Involved in several processes, including negative regulation of protein refolding; negative regulation of ubiquitin-protein transferase activity; and regulation of inclusion body assembly. Predicted to be located in inclusion body; mitochondrion; and perinuclear region of cytoplasm. Predicted to be active in cytosol; membrane; and nucleus. Orthologous to human BAG5 (BAG cochaperone 5). [provided by Alliance of Genome Resources, Apr 2022]

BAG5 Products (1)

mRNA Protein Name
NM_001008526.2 NP_001008526.1 BAG family molecular chaperone regulator 5

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21358815 RGD
enables protein-folding chaperone binding IDA
IDA: Inferred from direct assay
15603737 RGD
enables ubiquitin protein ligase binding IPI
IPI: Inferred from physical interaction
15603737 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of protein refolding IMP
IMP: Inferred from mutant phenotype
15603737 RGD
involved in negative regulation of protein ubiquitination IDA
IDA: Inferred from direct assay
15603737 RGD
involved in negative regulation of ubiquitin-protein transferase activity IDA
IDA: Inferred from direct assay
15603737 RGD
involved in regulation of inclusion body assembly IDA
IDA: Inferred from direct assay
15603737 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

BAG family molecular chaperone regulator 5

  • BAG-5

  • BCL2-associated athanogene 5

  • BCL2-associated athanogene 5-like 1

  • bcl-2-associated athanogene 5

BAG5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Bag5 Q5QJC9 STUB1 Homo sapiens Q9UNE7
SLC
21358815
Cross
Bag5 Q5QJC9 STUB1 Homo sapiens Q9UNE7
Pull Down
21358815
Cross
Bag5 Q5QJC9 STUB1 Homo sapiens Q9UNE7
Anti Tag CoIP
21358815
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01346 BAG5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22109 Bag5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28631 Bag5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens BAG5 NCBI NCBI:9529