Flrt1 - fibronectin leucine rich transmembrane protein 1 Gene

Also Known as D630040I23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 396184

Summary

Enables Fibroblast Growth Factor receptor binding activity. Involved in dendrite development; Fibroblast Growth Factor receptor signaling pathway; and neuron projection extension. Acts upstream of or within positive regulation of synapse assembly. Located in several cellular components, including neuron projection terminus; neuronal cell body membrane; and perinuclear region of cytoplasm. Is integral component of plasma membrane. Colocalizes with focal adhesion. Is expressed in several structures, including central nervous system; embryo mesenchyme; gut; neural ectoderm; and sensory organ. Orthologous to human FLRT1 (fibronectin leucine rich transmembrane protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Flrt1 Products (1)

mRNA Protein Name
NM_201411.2 NP_958813.1 leucine-rich repeat transmembrane protein FLRT1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables fibroblast growth factor receptor binding IPI
IPI: Inferred from physical interaction
16872596 MGI
Biological Process GO Annotation Evidence References Source
involved in dendrite development IMP
IMP: Inferred from mutant phenotype
20421966 MGI
involved in fibroblast growth factor receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
16872596 MGI
involved in neuron projection extension IMP
IMP: Inferred from mutant phenotype
20421966 MGI
acts upstream of or within positive regulation of synapse assembly IDA
IDA: Inferred from direct assay
24613359 MGI
Cellular Component GO Annotation Evidence References Source
located in cell-cell junction IDA
IDA: Inferred from direct assay
16872596 MGI
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
20421966 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
21673655 MGI
colocalizes with focal adhesion IDA
IDA: Inferred from direct assay
16872596 MGI
located in neuron projection terminus IDA
IDA: Inferred from direct assay
20421966 MGI
located in neuronal cell body membrane IDA
IDA: Inferred from direct assay
20421966 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
20421966 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
16872596 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucine-rich repeat transmembrane protein FLRT1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04984 FLRT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19194 Flrt1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25682 Flrt1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Flrt1 NCBI NCBI:23769