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CTLA4 - cytotoxic T-lymphocyte associated protein 4 Gene

Also Known as CD152

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding

Gene ID: 403696

About CTLA4

Primary_assembly 37: 12,528,644-12,590,422 forward strand.ROS_Cfam_1.0:CM025136.1

This gene has 3 transcripts (splice variants), 157 orthologues and 1 paralogue.

mRNA	Protein	Name
NM_001003106.1	NP_001003106.1	cytotoxic T-lymphocyte protein 4

IgV_CTLA-4

Protein Preferred Names	Protein Names
cytotoxic T-lymphocyte protein 4	CTLA-4 costimulatory molecule B7 receptor CD152 cytotoxic T-lymphocyte antigen 4 cytotoxic T-lymphocyte-associated antigen 4 soluble form of cytotoxic T-lymphocyte antigen 4

Cat. No.	Product Name	Accession	Purity
HY-P75320	CTLA-4 Protein, Canine (HEK293, His)	Q9GKP2 (K36-D161)	≥ 90%, as determined by reducing SDS-PAGE.
HY-P75321	CTLA-4 Protein, Canine (HEK293, Fc)	Q9GKP2 (K36-D161)	≥ 90%, as determined by reducing SDS-PAGE.

Inhibitory Antibodies (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-108829	Abatacept		≥99.0%	Unkown
HY-P9901	Ipilimumab	Inhibitor	99.88%	Unkown
HY-P9918	Tremelimumab		99.50%	Unkown

Inhibitory Antibodies (24)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99540	Tuvonralimab	Inhibitor	99.14%	Phase 4
HY-P99117	Cadonilimab	Inhibitor	99.87%	Phase 3
HY-P990042	Gotistobart	Inhibitor	≥99.0%	Phase 3
HY-P990690	Volrustomig	Inhibitor	≥99.0%	Phase 3
HY-P99484	Botensilimab	Inhibitor	99.00%	Phase 3
HY-P99166	Vudalimab	Inhibitor	≥99.0%	Phase 2
HY-P99714	Lorigerlimab	Inhibitor	97.5%	Phase 2
HY-P99514	Zalifrelimab	Inhibitor	98.28%	Phase 2
HY-P990048	Muzastotug	Inhibitor	99.48%	Phase 2
HY-P99809	Quavonlimab	Inhibitor	≥99.0%	Phase 2
HY-P990080	Sovipostobart	Inhibitor	96.528%	Phase 2
HY-P990739	Evalstotug		95.062%	Phase 2
HY-P990775	Vilastobart		99.63%	Phase 2
HY-P991566	KD6001	Inhibitor	/	Phase 2
HY-P991960	JS007		/	Phase 2
HY-P990703	Porustobart		99.70%	Phase 1
HY-P99844	Davoceticept		99.9%	Phase 1
HY-P990041	Firastotug	Inhibitor	98.62%	Phase 1
HY-P99709	Lodapolimab	Inhibitor	99.71%	Phase 1
HY-P99760	Nurulimab	Inhibitor	95.00%	Phase 1
HY-P99354	Bavunalimab		99.408%	Phase 1
HY-P991952	ADU-1604	Inhibitor	/	Phase 1
HY-P991953	BAT4706		/	Phase 1
HY-P991961	REGN4659	Inhibitor	/	Phase 1

Bioactive Molecules (7)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-159692	AZD8701	Inhibitor	96.61%	Unkown
HY-120120	DZ-2384	Inhibitor	/	Unkown
HY-122081	CPI-644	Inhibitor	/	Unkown
HY-RS03299	CTLA4 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS03300	Ctla4 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS03301	Ctla4 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-179228	AN02		/	Unkown

Inhibitory Antibodies (17)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P99132	Anti-Mouse CTLA-4 Antibody (9D9)	Inhibitor	98.91%	Unkown
HY-108829A	Abatacept (powder)	Inhibitor	99.01%	Unkown
HY-P990789	Anti-Mouse CTLA-4 Antibody (9H10)	Inhibitor	99%	Unkown
HY-P99943	Erfonrilimab		99.98%	Unkown
HY-P990256	Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9)	Inhibitor	98.68%	Unkown
HY-P990945	Tazlestobart		99.66%	Unkown
HY-P990722	Danvilostomig		98.38%	Unkown
HY-P991139	Futermestotug	Inhibitor	99.84%	Unkown
HY-P990848	Anti-CTLA-4/CD152 Antibody (BN13)	Inhibitor	/	Unkown
HY-P991951	ABA04		/	Unkown
HY-P991959	JMW-3B3	Inhibitor	/	Unkown
HY-P992062	Anti-Mouse CD80 Antibody (TKMG48)	Agonist	/	Unkown
HY-P992177	AI-025	Inhibitor	/	Unkown
HY-P992511	CS2009	Inhibitor	/	Unkown
HY-P991775	Anti-Rat CTLA-4 Antibody (WKH203)	Inhibitor	/	Unkown
HY-P991827	Anti-Mouse CTLA-4 Antibody (UC10-4F10-11)	Inhibitor	/	Unkown
HY-P991958	GIGA-564	Inhibitor	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	CTLA4	NCBI	NCBI:1493