MEA1 - male-enhanced antigen 1 Gene

Also Known as HYS; MEA

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 4201

About MEA1

Cytogenetic location: 6p21.1 Genomic coordinates (GRCh38): 6:43,011,143-43,016,886 (from NCBI)

This gene has 6 transcripts (splice variants) and 227 orthologues. Broad expression in testis (RPKM 41.1), brain (RPKM 13.3) and 25 other tissues.

Summary

Predicted to be involved in male gonad development. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

MEA1 Products (4)

mRNA Protein Name
NM_001318942.1 NP_001305871.1 male-enhanced antigen 1 isoform 2
NM_001318943.1 NP_001305872.1 male-enhanced antigen 1 isoform 2
NM_001363578.1 NP_001350507.1 male-enhanced antigen 1 isoform 3
NM_014623.4 NP_055438.1 male-enhanced antigen 1 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MEA1 Protein Structure

MEA1

MEA1: Male enhanced antigen 1 (MEA1) (14 - 185)

  • 0
  • 100
  • 185 a.a.
Protein Preferred Names Protein Names

male-enhanced antigen 1

  • Male-enhanced antigen (H-Y structural gene)

MEA1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
MEA1 Q16626 AP1M1 Homo sapiens Q9BXS5
Anti Tag CoIP
33961781
Intra
MEA1 Q16626 AP1M1 Homo sapiens Q9BXS5
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
African Histoplasmosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08273 MEA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus MEA1 RGD RGD:1597751
Mus musculus MEA1 MGD MGI:96957
Canis familiaris MEA1 VGNC VGNC:43112
Macaca mulatta MEA1 VGNC VGNC:74696
Others MEA1 NCBI