IFIT1B - interferon induced protein with tetratricopeptide repeats 1B Gene

Also Known as IFIT1L; bA149I23.6

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 439996

About IFIT1B

This gene has 1 transcript (splice variant), 508 orthologues and 4 paralogues. Restricted expression toward bone marrow (RPKM 10.2).

Summary

Predicted to enable RNA binding activity. Predicted to be involved in defense response to virus. Predicted to act upstream of or within cellular response to interferon-alpha; cellular response to interferon-beta; and response to bacterium. Predicted to be located in cytoplasm. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

IFIT1B Products (1)

mRNA Protein Name
NM_001010987.2 NP_001010987.1 interferon-induced protein with tetratricopeptide repeats 1B

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21642987 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IFIT1B Protein Structure

TPR_12

TPR_12: Tetratricopeptide repeat (54 - 125)

TPR_2

TPR_2: Tetratricopeptide repeat (155 - 174)

TPR_7

TPR_7: Tetratricopeptide repeat (342 - 370)

TPR_1

TPR_1: Tetratricopeptide repeat (443 - 467)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 474 a.a.
Protein Preferred Names Protein Names

interferon-induced protein with tetratricopeptide repeats 1B

  • interferon-induced protein with tetratricopeptide repeats 1-like protein

IFIT1B Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
IFIT1B Q5T764 IFIT3 Homo sapiens O14879
Y2H Array
32296183
Intra
IFIT1B Q5T764 IFIT3 Homo sapiens O14879
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06561 IFIT1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus IFIT1B RGD RGD:620599
Others IFIT1B NCBI