Nmb - neuromedin B Gene

Also Known as RGD1562710

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 499194

Summary

Enables neuromedin B receptor binding activity. Involved in several processes, including arachidonic acid secretion; glucose homeostasis; and regulation of hormone secretion. Located in neuron projection. Biomarker of obesity. Human ortholog(s) of this gene implicated in obesity. Orthologous to human NMB (neuromedin B). [provided by Alliance of Genome Resources, Apr 2022]

Nmb Products (1)

mRNA Protein Name
NM_001109149.1 NP_001102619.1 neuromedin-B precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables neuromedin B receptor binding IPI
IPI: Inferred from physical interaction
1326946 RGD
Biological Process GO Annotation Evidence References Source
involved in arachidonate secretion IDA
IDA: Inferred from direct assay
8532598 RGD
involved in negative regulation of hormone secretion IMP
IMP: Inferred from mutant phenotype
1557409 RGD
involved in positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
8532598 RGD
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: Inferred from direct assay
8532598 RGD
involved in positive regulation of hormone secretion IDA
IDA: Inferred from direct assay
8136736 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuromedin-B

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-141604 Glembatumumab vedotin Inhibitor ≥99.0% Phase 2

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P0241 Neuromedin B 99.22% Unkown
HY-116216 PD 168368 Antagonist ≥99.0% Unkown
HY-103277A BIM 23042 TFA Antagonist 99.75% Unkown
HY-RS05648 GPNMB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09368 NMB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-103277 BIM 23042 Antagonist / Unkown
HY-125075 PD 165929 Antagonist / Unkown
HY-17674 Bombesin receptor antagonist-1 Antagonist / Unkown
HY-RS17137 Nmb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23583 Nmb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992424 NMB04 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nmb NCBI NCBI:4828