PABPC3 - poly(A) binding protein cytoplasmic 3 Gene

Homo sapiens

Also known as PABP3; tPABP; PABPL3

Gene ID: 5042 | Gene type: protein coding

About PABPC3

Cytogenetic location: 13q12.13 Genomic coordinates (GRCh38): 13:25,096,136-25,099,254 (from NCBI)

This gene has 1 transcript (splice variant), 108 orthologues and 24 paralogues.

Summary

Messenger RNA stability and translation initiation are extensively under the control of poly(A)-binding proteins (PABP). See PABPC1 (MIM 604679) for background information.[supplied by OMIM, Jul 2002]

PABPC3 Products(1)

mRNA	Protein	Name
NM_030979.3	NP_112241.2	polyadenylate-binding protein 3

PABPC3 Protein Structure

RRM_1

PABP

0
100
200
300
400
500
631 a.a.

Protein Preferred Names

Protein Names

polyadenylate-binding protein 3

PABP-3

Related Diseases

Diseases

Alias

Polyposis, Skin Pigmentation, Alopecia, And Fingernail Changes

Cronkhite-Canada Syndrome	Gastric Cronkhite Canada Polyposis
Cronkhite-Canada Disease	Polyposis Skin Pigmentation Alopecia Fingernail Changes
Gastrointestinal Polyposis-Ectodermal Changes Syndrome	Gastrointestinal Polyposis-Skin Pigmentation-Alopecia-Fingernail Changes Syndrome
Polyposis, Gastrointestinal, With Ectodermal Changes

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09949	PABPC3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PABPC3	RGD	RGD:1311201
Macaca mulatta	PABPC3	VGNC	VGNC:106280
Mus musculus	PABPC3	MGD	MGI:1349722

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