COPS7A - COP9 signalosome subunit 7A Gene

Also Known as CSN7; CSN7A; SGN7a

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 50813

Summary

This gene encodes a component of the COP9 signalosome, an evolutionarily conserved multi-subunit Protease that regulates the activity of the ubiquitin conjugation pathway. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Mar 2014]
Ubiquitous expression in brain (RPKM 27.2), thyroid (RPKM 23.7) and 25 other tissues.

COPS7A Products (1)

mRNA Protein Name
NG_034023.1 [RefSeqGene]

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
20399188 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in protein deneddylation IDA
IDA: Inferred from direct assay
19141280 GOA
Cellular Component GO Annotation Evidence Verweise Source
part of COP9 signalosome IDA
IDA: Inferred from direct assay
18850735 GOA
part of COP9 signalosome IPI
IPI: Inferred from physical interaction
25043011 GOA
located in cytoplasm IDA
IDA: Inferred from direct assay
24421388 GOA
located in nucleus IDA
IDA: Inferred from direct assay
24421388 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

COPS7A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
COPS7A Q9UBW8 COPS3 Homo sapiens Q9UNS2
Anti Tag CoIP
26496610
Cross: Cross-species interaction Intra: Intraspecies interaction