2. Gene
  3. CDK17 - cyclin dependent kinase 17 Gene

CDK17 - cyclin dependent kinase 17 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PCTK2; PCTAIRE2

Gene ID: 5128 | Gene type: protein coding

About CDK17

Cytogenetic location: 12q23.1 Genomic coordinates (GRCh38): 12:96,278,225-96,400,439 (from NCBI)

This gene has 12 transcripts (splice variants), 268 orthologues and 26 paralogues. Ubiquitous expression in brain (RPKM 21.3), testis (RPKM 15.1) and 24 other tissues.

Summary

The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It has similarity to a rat protein that is thought to play a role in terminally differentiated neurons. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jul 2010]

CDK17 Products(2)

mRNA Protein Name
NM_001170464.4 NP_001163935.1 cyclin-dependent kinase 17 isoform 2
NM_002595.5 NP_002586.2 cyclin-dependent kinase 17 isoform 1

CDK17 Protein Structure

Pkinase

Pkinase: Protein kinase domain (193 - 473)

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  • 523 a.a.
Protein Preferred Names Protein Names

cyclin-dependent kinase 17

PCTAIRE-motif protein kinase 2

Related Diseases

Diseases Alias
Spastic Paraplegia 16, X-Linked

SPG16

Hereditary Spastic Paraplegia 16

X-Linked Spastic Paraplegia Type 16

Spastic Paraplegia 16, X-Linked, Complicated

X-Linked Spastic Paraplegia 16

Spastic Paraplegia 16

Spastic Paraplegia-16, X-Linked, Complicated
Spastic Paraplegia 12, Autosomal Dominant

SPG12

Hereditary Spastic Paraplegia 12

Autosomal Dominant Spastic Paraplegia Type 12

Autosomal Dominant Spastic Paraplegia 12

Spastic Paraplegia 12

Spastic Paraplegia-12

Paraplegia, Spastic, Autosomal Dominant, Type 12
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-137346 DD-03-156 99.63% Unkown
HY-RS02369 CDK17 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CDK17 VGNC VGNC:108225
Felis catus CDK17 VGNC VGNC:68736
Macaca mulatta CDK17 VGNC VGNC:71161
Rattus norvegicus CDK17 RGD RGD:1565593
Mus musculus CDK17 MGD MGI:97517
Bos taurus CDK17 VGNC VGNC:27120
Others CDK17 NCBI