CEND1 - cell cycle exit and neuronal differentiation 1 Gene

Also Known as BM88

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51286

About CEND1

Cytogenetic location: 11p15.5 Genomic coordinates (GRCh38): 11:787,115-790,090 (from NCBI)

This gene has 2 transcripts (splice variants) and 70 orthologues. Biased expression in brain (RPKM 37.5) and adrenal (RPKM 2.6).

Summary

The protein encoded by this gene is a neuron-specific protein. The similar protein in pig enhances neuroblastoma cell differentiation in vitro and may be involved in neuronal differentiation in vivo. Multiple pseudogenes have been reported for this gene. [provided by RefSeq, Jul 2008]

CEND1 Products (1)

mRNA Protein Name
NM_016564.4 NP_057648.2 cell cycle exit and neuronal differentiation protein 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
30177828 GOA
Cellular Component GO Annotation Evidence References Source
colocalizes with mitochondrion IDA
IDA: Inferred from direct assay
11311134 GOA
colocalizes with vesicle IDA
IDA: Inferred from direct assay
11311134 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cell cycle exit and neuronal differentiation protein 1

  • BM88 antigen

CEND1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CEND1 Q8N111 MFF Homo sapiens Q9GZY8-5
Validated Y2H
32296183
Intra
CEND1 Q8N111 MAGED4B Homo sapiens Q96JG8
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

CEND1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P82384 CEND1 Antibody (YA2129) WB, IHC-P, ICC/IF, IP Human, Mouse, Rat

Related Diseases

Diseases Alias
Beckwith-Wiedemann Syndrome

  • Wiedemann-Beckwith Syndrome

  • BWS

  • Exomphalos-Macroglossia-Gigantism Syndrome

  • Emg Syndrome

  • Beckwith-Wiedemann Syndrome Due To Cdkn1c Mutation

  • Emg Abnormality

  • Wbs

  • Exomphalos Macroglossia Gigantism Syndrome

  • Beckwith-Wiedemann Syndrome Due To Nsd1 Mutation

  • Macroglossia Exomphalos Gigantism
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-P3448 Certepetide Activator 99.80% Phase 2

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02472 CEND1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-P3448S Certepetide-13C6,15N2 Activator / Unkown
HY-P3448S1 Certepetide-13C2,15N Activator / Unkown
HY-RS17604 Cend1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24064 Cend1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CEND1 VGNC VGNC:81994
Mus musculus CEND1 MGD MGI:1929898
Canis familiaris CEND1 VGNC VGNC:39100
Rattus norvegicus CEND1 RGD RGD:1309401
Bos taurus CEND1 VGNC VGNC:27173
Others CEND1 NCBI