1. Gene
  2. CTDSPL2 - CTD small phosphatase like 2 Gene

CTDSPL2 - CTD small phosphatase like 2 Gene

Homo sapiens

Also known as SCP4; HSPC058; HSPC129

Gene ID: 51496 | Gene type: protein coding

About CTDSPL2

Cytogenetic location: 15q15.3-q21.1 Genomic coordinates (GRCh38): 15:44,427,629-44,529,038 (from NCBI)

This gene has 11 transcripts (splice variants), 281 orthologues and 5 paralogues. Ubiquitous expression in lymph node (RPKM 7.7), testis (RPKM 7.5) and 25 other tissues.

Summary

Enables RNA polymerase II CTD heptapeptide repeat Phosphatase activity. Predicted to act upstream of or within negative regulation of BMP signaling pathway; positive regulation of protein export from nucleus; and protein dephosphorylation. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CTDSPL2 Products(1)

mRNA Protein Name
NM_016396.3 NP_057480.2 CTD small phosphatase-like protein 2

CTDSPL2 Protein Structure

NIF

NIF: NLI interacting factor-like phosphatase (289 - 450)

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  • 466 a.a.
Protein Preferred Names Protein Names

CTD small phosphatase-like protein 2

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2

Orthologs Information

Species Symbol Source ID
Bos taurus CTDSPL2 VGNC VGNC:27792
Rattus norvegicus CTDSPL2 RGD RGD:1309219
Canis familiaris CTDSPL2 VGNC VGNC:39695
Macaca mulatta CTDSPL2 VGNC VGNC:71593
Felis catus CTDSPL2 VGNC VGNC:80993
Mus musculus CTDSPL2 MGD MGI:1196405