ARMCX3 - armadillo repeat containing X-linked 3 Gene

Also Known as ALEX3; GASP6; dJ545K15.2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51566

About ARMCX3

Cytogenetic location: Xq22.1 Genomic coordinates (GRCh38): X:101,623,151-101,627,843 (from NCBI)

This gene has 7 transcripts (splice variants), 151 orthologues and 11 paralogues. Ubiquitous expression in adrenal (RPKM 17.0), thyroid (RPKM 15.9) and 25 other tissues.

Summary

This gene encodes a member of the ALEX family of proteins which may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with Other family members on the X chromosome. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]

ARMCX3 Products (3)

mRNA Protein Name
NM_016607.4 NP_057691.1 armadillo repeat-containing X-linked protein 3
NM_177947.3 NP_808816.1 armadillo repeat-containing X-linked protein 3
NM_177948.3 NP_808817.1 armadillo repeat-containing X-linked protein 3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19060904 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ARMCX3 Protein Structure

Arm_2

Arm_2: Armadillo-like (111 - 362)

  • 0
  • 100
  • 200
  • 300
  • 379 a.a.
Protein Preferred Names Protein Names

armadillo repeat-containing X-linked protein 3

  • 1200004E24Rik

ARMCX3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ARMCX3 Q9UH62 FAM25C Homo sapiens B3EWG5
Y2H Prey Pooling
32296183
Intra
ARMCX3 Q9UH62 FAM25C Homo sapiens B3EWG5
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01008 ARMCX3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ARMCX3 VGNC VGNC:50548
Canis familiaris ARMCX3 VGNC VGNC:54661
Mus musculus ARMCX3 MGD MGI:1918953
Rattus norvegicus ARMCX3 RGD RGD:1549739
Others ARMCX3 NCBI