2. Gene
  3. CYRIB - CYFIP related Rac1 interactor B Gene

CYRIB - CYFIP related Rac1 interactor B Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as L1; CYRI; BM-009; CYRI-B; FAM49B

Gene ID: 51571 | Gene type: protein coding

About CYRIB

Cytogenetic location: 8q24.21 Genomic coordinates (GRCh38): 8:129,839,593-130,017,129 (from NCBI)

This gene has 31 transcripts (splice variants), 274 orthologues and 1 paralogue. Broad expression in bone marrow (RPKM 26.7), appendix (RPKM 26.4) and 24 other tissues.

Summary

Enables small GTPase binding activity. Involved in several processes, including cellular response to molecule of Bacterial origin; negative regulation of small GTPase mediated signal transduction; and regulation of organelle organization. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

CYRIB Products(78)

mRNA Protein Name
NM_001256763.2 NP_001243692.1 CYFIP-related Rac1 interactor B isoform 1
NM_001330612.2 NP_001317541.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353242.2 NP_001340171.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353243.2 NP_001340172.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353244.2 NP_001340173.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353245.1 NP_001340174.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353246.1 NP_001340175.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353247.1 NP_001340176.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353248.2 NP_001340177.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353249.1 NP_001340178.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353250.1 NP_001340179.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353251.1 NP_001340180.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353252.1 NP_001340181.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353253.1 NP_001340182.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353254.2 NP_001340183.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353255.1 NP_001340184.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353256.2 NP_001340185.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353257.2 NP_001340186.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353258.2 NP_001340187.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353259.2 NP_001340188.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353260.2 NP_001340189.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353261.2 NP_001340190.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353262.2 NP_001340191.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353263.2 NP_001340192.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353264.2 NP_001340193.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353265.2 NP_001340194.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353266.2 NP_001340195.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353267.2 NP_001340196.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353268.2 NP_001340197.1 CYFIP-related Rac1 interactor B isoform 1
NM_001353269.1 NP_001340198.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353270.1 NP_001340199.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353271.1 NP_001340200.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353272.1 NP_001340201.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353273.1 NP_001340202.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353274.1 NP_001340203.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353275.1 NP_001340204.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353276.2 NP_001340205.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353277.1 NP_001340206.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353278.1 NP_001340207.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353279.1 NP_001340208.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353280.1 NP_001340209.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353281.1 NP_001340210.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353282.2 NP_001340211.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353283.2 NP_001340212.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353284.2 NP_001340213.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353285.2 NP_001340214.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353286.2 NP_001340215.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353287.2 NP_001340216.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353288.2 NP_001340217.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353289.2 NP_001340218.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353290.2 NP_001340219.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353291.2 NP_001340220.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353292.2 NP_001340221.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353293.2 NP_001340222.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353294.2 NP_001340223.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353295.2 NP_001340224.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353296.2 NP_001340225.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353297.2 NP_001340226.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353298.2 NP_001340227.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353299.2 NP_001340228.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353300.2 NP_001340229.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353301.2 NP_001340230.1 CYFIP-related Rac1 interactor B isoform 2
NM_001353302.1 NP_001340231.1 CYFIP-related Rac1 interactor B isoform 3
NM_001353303.1 NP_001340232.1 CYFIP-related Rac1 interactor B isoform 3
NM_001353304.1 NP_001340233.1 CYFIP-related Rac1 interactor B isoform 3
NM_001353305.1 NP_001340234.1 CYFIP-related Rac1 interactor B isoform 3
NM_001353306.2 NP_001340235.1 CYFIP-related Rac1 interactor B isoform 3
NM_001353307.2 NP_001340236.1 CYFIP-related Rac1 interactor B isoform 3
NM_001353308.1 NP_001340237.1 CYFIP-related Rac1 interactor B isoform 3
NM_001353309.1 NP_001340238.1 CYFIP-related Rac1 interactor B isoform 3
NM_001353310.2 NP_001340239.1 CYFIP-related Rac1 interactor B isoform 3
NM_001353311.2 NP_001340240.1 CYFIP-related Rac1 interactor B isoform 3
NM_001353312.2 NP_001340241.1 CYFIP-related Rac1 interactor B isoform 3
NM_001353313.2 NP_001340242.1 CYFIP-related Rac1 interactor B isoform 3
NM_001353314.2 NP_001340243.1 CYFIP-related Rac1 interactor B isoform 3
NM_001353315.2 NP_001340244.1 CYFIP-related Rac1 interactor B isoform 3
NM_001353316.2 NP_001340245.1 CYFIP-related Rac1 interactor B isoform 4
NM_016623.5 NP_057707.3 CYFIP-related Rac1 interactor B isoform 1

CYRIB Protein Structure

DUF1394

DUF1394: Protein of unknown function (DUF1394) (17 - 320)

  • 0
  • 100
  • 200
  • 300
  • 324 a.a.
Protein Preferred Names Protein Names

CYFIP-related Rac1 interactor B

FAM49B/JPH1 fusion

Related Diseases

Diseases Alias
Cardiomyopathy, Dilated, 3b

Dilated Cardiomyopathy 3b

CMD3B

X-Linked Dilated Cardiomyopathy

Xlcm

Dmd-Associated Dilated Cardiomyopathy

Cardiomyopathy, Dilated, X-Linked

Dmd-Related Dilated Cardiomyopathy

Xldc

Cardiomyopathy, Dilated, X-Linked 3b

Cardiomyopathy, Dilated, Type 3b
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03492 CYRIB Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CYRIB RGD RGD:1307697
Mus musculus CYRIB MGD MGI:1923520
Felis catus CYRIB VGNC VGNC:62115
Canis familiaris CYRIB VGNC VGNC:40686
Macaca mulatta CYRIB VGNC VGNC:72345
Bos taurus CYRIB VGNC VGNC:28819