MTMR12 - myotubularin related protein 12 Gene

Also Known as 3-PAP; PIP3AP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 54545

Summary

Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol 3-phosphate (PtdIns(3)P), regulate diverse cellular processes. The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns(3)P 3-phosphatase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Ubiquitous expression in testis (RPKM 14.2), lung (RPKM 9.9) and 25 other tissues.

MTMR12 Products (3)

mRNA Protein Name
NM_001040446.3 NP_001035536.1 myotubularin-related protein 12 isoform 1
NM_001294343.2 NP_001281272.1 myotubularin-related protein 12 isoform 2
NM_001294344.2 NP_001281273.1 myotubularin-related protein 12 isoform 3

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12847286 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
16787938 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MTMR12 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
MTMR12 Q9C0I1 MTM1 Homo sapiens Q13496
Anti Bait CoIP
12847286
Intra
MTMR12 Q9C0I1 MTMR2 Homo sapiens Q13614
Anti Tag CoIP
12847286
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08785 MTMR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08786 MTMR10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08787 MTMR11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08788 MTMR14 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08789 MTMR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown