SDK2 - sidekick cell adhesion molecule 2 Gene

Homo sapiens

Gene ID: 54549 | Gene type: protein coding

About SDK2

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:73,334,384-73,644,445 (from NCBI)

This gene has 5 transcripts (splice variants), 197 orthologues and 36 paralogues. Biased expression in testis (RPKM 6.4), spleen (RPKM 1.7) and 8 other tissues.

Summary

The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains two immunoglobulin domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. This protein, and a homologous mouse sequence, are very similar to the Drosophila sidekick gene product but the specific function of this superfamily member is not yet known. Evidence for alternative splicing at this gene locus has been observed but the full-length nature of additional variants has not yet been determined. [provided by RefSeq, Jul 2008]

SDK2 Products(1)

mRNA	Protein	Name
NM_001144952.2	NP_001138424.1	protein sidekick-2 precursor

SDK2 Protein Structure

I-set

Ig_2

I-set

fn3

0
400
800
1200
1600
2000
2172 a.a.

Protein Preferred Names

Protein Names

protein sidekick-2

sidekick homolog 2

Related Diseases

Diseases

Alias

Patellar Tendinitis

Patellar Tendonitis

Panic Disorder

Panic Anxiety Syndrome	Panic
Panic Disorder 1	Episodic Paroxysmal Anxiety Disorder

Brachyolmia

Brachyrachia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12596	SDK2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	SDK2	VGNC	VGNC:64954
Mus musculus	SDK2	MGD	MGI:2443847
Macaca mulatta	SDK2	VGNC	VGNC:99225
Rattus norvegicus	SDK2	RGD	RGD:1310397
Canis familiaris	SDK2	VGNC	VGNC:45954
Bos taurus	SDK2	VGNC	VGNC:34394