Pdgfc - platelet-derived growth factor, C polypeptide Gene

Also Known as SCDGF; PDGF-C; VEGF-E; 1110064L01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54635

Summary

Enables platelet-derived growth factor receptor binding activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including cellular response to amino acid stimulus; platelet-derived growth factor receptor signaling pathway; and regulation of protein phosphorylation. Located in extracellular region. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human PDGFC (platelet derived growth factor C). [provided by Alliance of Genome Resources, Apr 2022]

Pdgfc Products (2)

mRNA Protein Name
NM_001357746.1 NP_001344675.1 platelet-derived growth factor C isoform 2
NM_019971.3 NP_064355.1 platelet-derived growth factor C isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables platelet-derived growth factor receptor binding IDA
IDA: Inferred from direct assay
10806482 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within activation of transmembrane receptor protein tyrosine kinase activity IDA
IDA: Inferred from direct assay
10806482 MGI
acts upstream of or within animal organ morphogenesis IGI
IGI: Inferred from genetic interaction
15361870 MGI
acts upstream of or within animal organ morphogenesis IMP
IMP: Inferred from mutant phenotype
15361870 MGI
acts upstream of or within bone development IGI
IGI: Inferred from genetic interaction
23938297 MGI
acts upstream of or within cellular response to amino acid stimulus IDA
IDA: Inferred from direct assay
20548288 MGI
acts upstream of or within digestive tract development IGI
IGI: Inferred from genetic interaction
23938297 MGI
acts upstream of fibroblast proliferation IDA
IDA: Inferred from direct assay
15234987 MGI
acts upstream of or within platelet-derived growth factor receptor signaling pathway IDA
IDA: Inferred from direct assay
15372073 MGI
acts upstream of or within positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
10806482 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: Inferred from mutant phenotype
27492130 MGI
acts upstream of or within positive regulation of fibroblast proliferation IDA
IDA: Inferred from direct assay
15234987 MGI
acts upstream of or within regulation of peptidyl-tyrosine phosphorylation IDA
IDA: Inferred from direct assay
11940581 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular region IDA
IDA: Inferred from direct assay
10806482 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

platelet-derived growth factor C

  • fallotein

  • spinal cord-derived growth factor

Recombinant Pdgfc Proteins

Cat. No. Product Name Accession Purity
HY-P73354 PDGF-CC Protein, Mouse (HEK293, Fc) Q8CI19 (V235-G345) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73719 PDGF-CC Protein, Mouse (P.pastoris, His) Q8CI19 (V235-G345) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10252 PDGFC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174551 Human PDGFC mRNA / Unkown
HY-RS21686 Pdgfc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28204 Pdgfc Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdgfc NCBI NCBI:56034