ACP3 - acid phosphatase 3 Gene

Homo sapiens

Also known as ACPP; 5'-NT; ACP-3; TM-PAP

Gene ID: 55 | Gene type: protein coding

About ACP3

Cytogenetic location: 3q22.1 Genomic coordinates (GRCh38): 3:132,317,407-132,368,302 (from NCBI)

This gene has 9 transcripts (splice variants), 165 orthologues and 5 paralogues. Restricted expression toward prostate (RPKM 1149.8).

Summary

This gene encodes an Enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq, Sep 2008]

ACP3 Products(3)

mRNA	Protein	Name
NM_001099.5	NP_001090.2	prostatic acid phosphatase isoform PAP precursor
NM_001134194.2	NP_001127666.1	prostatic acid phosphatase isoform TM-PAP precursor
NM_001292037.2	NP_001278966.1	prostatic acid phosphatase isoform 3

ACP3 Protein Structure

His_Phos_2

0
100
200
300
386 a.a.

Protein Preferred Names

Protein Names

prostatic acid phosphatase

TMPase

Recombinant ACP3 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7817	Prostatic acid phosphatase/ACPP Protein, Human (354a.a, HEK293, His, solution)	AAH16344.1 (K33-D386)	≥95%
HY-P73382	Prostatic acid Phosphatase/ACPP Protein, Human (382a.a, HEK293, His)	P15309 (M1-K382)	≥95%
HY-P7817A	Prostatic acid phosphatase/ACPP Protein, Human (HEK293, His)	NP_001127666.1 (K33-K382)	≥95%
HY-P700619	Prostatic acid Phosphatase/ACPP Protein, Human (HEK293, GFP-His)	P15309 (K33-K382)	≥95%
HY-P700620	Prostatic acid Phosphatase/ACPP Protein-VLP, Human (386a.a, HEK293, His)	P15309 (K33-I418)	≥95%

Related Diseases

Diseases

Alias

Prostatitis

Clear Cell Adenocarcinoma

Mesonephroma	Water-Clear Cell Adenocarcinoma
Adenocarcinoma, Clear Cell	Malignant Mesonephroma
Mesonephroid Clear Cell Carcinoma	Mesonephroma, Malignant
Water-Clear Cell Carcinoma	Wolffian Duct Neoplasm
Adenocarcinoma Clear Cell	Mesonephric Tumor

Atypical Choroid Plexus Papilloma

Atypical Papilloma Of Choroid Plexus

Atypical Cpp

Cerebrovascular Benign Neoplasm

Phosphatase, Acid, Of Tissues

Lysosomal Acid Phosphatase

Acp3--Alpha Polypeptide

Choroid Plexus Cancer

Choroid Plexus Carcinoma	Choroid Plexus Neoplasms
Choroid Plexus Neoplasm	Tumor Of Choroid Plexus
Tumor Of The Choroid Plexus	Choroid Plexus Tumor
Choroid Plexus Tumors	Anaplastic Choroid Plexus Papilloma
Choroid Plexus Papilloma Nos	Papilloma Of Choroid Plexus
Plexus Choroideus Papilloma	Choroid Plexus Papilloma In Fourth Ventricle
Plexus Choroideus Papilloma In Fourth Ventricle

Prostatic Hyperplasia, Benign

Benign Prostatic Hyperplasia	BPH
Prostatic Hyperplasia

Prostatic Adenoma

Prostatic Hyperplasia	Adenoma - Prostate
Adenoma Of Prostate	Benign Adenoma Of Prostate
Prostate Adenoma	Benign Prostatic Hyperplasia

Prostate Cancer

Prostate Carcinoma	Prostate Cancer, Familial
Prostate Neoplasm	Prostate Cancer, Somatic
Prostate Cancer, Susceptibility To	Prostatic Cancer
Prostatic Neoplasms	Hereditary Prostate Cancer
Prostatic Neoplasm	Cancer Of Prostate
Carcinoma Of Prostate	Familial Prostate Cancer
Familial Prostate Carcinoma	Malignant Tumor Of Prostate
Malignant Neoplasm Of Prostate	Prostate Cancer, Familial, Susceptibility To
Malignant Tumor Of The Prostate	Ngp - New Growth Of Prostate
Tumor Of The Prostate	Prostate Cancer, Hereditary
Cancer Of The Prostate	Malignant Neoplasm Of The Prostate
Prostatic Carcinoma	PC
Prca	Cancer, Prostate
Malignant Prostatic Tumour	Malignant Tumour Of Prostate
Primary Prostate Cancer	Primary Malignant Neoplasm Of Prostate
Prostate Gland Cancer

Combined Oxidative Phosphorylation Deficiency 17

COXPD17	Combined Oxidative Phosphorylation Defect Type 17
Combined Oxidative Phosphorylation Deficiency, Type 17

Prostate Disease

Prostatic Diseases

Prostate Diseases

Papilloma Of Choroid Plexus

Choroid Plexus Papilloma	CPP
Childhood Choroid Plexus Papilloma	Papilloma Choroid Plexus
Papilloma, Choroid Plexus	Choroid Plexus Carcinoma

Endodermal Sinus Tumor

Yolk Sac Tumor	Endodermal Sinus Tumour
Hepatoid Yolk Sac Tumour	Infantile Embryonal Carcinoma
Yolk Sac Neoplasm	Yolk Sac Tumour

Cerebral Ventricle Cancer

Cerebral Ventricle Neoplasms	Cerebral Ventricle Neoplasm
Intraventricular Tumor Of Brain

Cerebrum Cancer

Cerebral Cancer	Neoplasm Of Cerebrum
Tumor Of Cerebrum	Malignant Neoplasm Of Cerebrum

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00188	ACP3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ACP3	RGD	RGD:2023
Bos taurus	ACP3	VGNC	VGNC:52603
Canis familiaris	ACP3	VGNC	VGNC:54915
Mus musculus	ACP3	MGD	MGI:1928480
Macaca mulatta	ACP3	VGNC	VGNC:69385
Felis catus	ACP3	VGNC	VGNC:59528
Others	ACP3	NCBI