17 Results for "

55049

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "55049" in MCE Product Catalog:

18
18 Publications Verification
Cat. No.: HY-134581
CAS No.: 2101938-42-3
Purity:  99.80%
Synonyms: M5049
Research Areas:  

Inflammation/Immunology

Enpatoran (M5049) is a potent, orally active and dual TLR7/8 inhibitor with IC50s of 11.1 nM and 24.1 nM in HEK293 cells, respectively. Enpatoran is inactive against TLR3, TLR4 and TLR9. Enpatoran can block molecule synthetic ligands and natural endogenous RNA ligands. Enpatoran exhibits excellent pharmacokinetic properties in vivo. Enpatoran can be used for both innate and adaptive autoimmunity blocking research .
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18
18 Publications Verification
Cat. No.: HY-134581A
CAS No.: 2101945-93-9
Purity:  99.42%
Synonyms: M5049 hydrochloride
Research Areas:  

Inflammation/Immunology

Enpatoran (M5049) hydrochloride is a potent, orally active and dual TLR7/8 inhibitor with IC50s of 11.1 nM and 24.1 nM in HEK293 cells, respectively. Enpatoran hydrochloride is inactive against TLR3, TLR4 and TLR9. Enpatoran hydrochloride can block molecule synthetic ligands and natural endogenous RNA ligands. Enpatoran hydrochloride exhibits excellent pharmacokinetic properties in vivo. Enpatoran hydrochloride can be used for both innate and adaptive autoimmunity blocking research .
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10
10 Cited Publications
Cat. No.: HY-50934
CAS No.: 112522-64-2
Synonyms: N-acetyldinaline; CI-994; Goe-5549
Target:  

HDAC Apoptosis

Research Areas:  

Cancer

Tacedinaline (N-acetyldinaline) is an inhibitor of the histone deacetylase (HDAC) with IC50s of 0.9, 0.9, 1.2 μM for recombinant HDAC 1, 2 and 3 respectively.
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1
1 Cited Publications
Cat. No.: HY-108526
CAS No.: 59662-49-6
Purity:  99.70%
Target:  

RAR/RXR Autophagy

Research Areas:  

Others

AC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of 6.9.
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Cat. No.: HY-W272217S
CAS No.: 16416-33-4
Synonyms: n-Octacosane-d58; NSC 5549-d58
Octacosane-d58 is the deuterium labeled Octacosane . Octacosane is an endogenous metabolite with antibacterial activity. Octacosane shows high cytotoxicity against murine melanoma B16F10-Nex2 cells besides inducing protection against a grafted subcutaneous melanoma. Octacosane has the larvicidal activity against mosquito Culex quinquefasciatus with the LC50 concentration of 7.2 mg/l .
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Cat. No.: HY-W272217
CAS No.: 630-02-4
Synonyms: n-Octacosane; NSC 5549
Octacosane is an endogenous metabolite with antibacterial activity. Octacosane shows high cytotoxicity against murine melanoma B16F10-Nex2 cells besides inducing protection against a grafted subcutaneous melanoma. Octacosane has the larvicidal activity against mosquito Culex quinquefasciatus with the LC50 concentration of 7.2 mg/l .
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Cat. No.: HY-W272217R
CAS No.: 630-02-4
Synonyms: n-Octacosane (Standard); NSC 5549 (Standard)
Octacosane (Standard) is the analytical standard of Octacosane. This product is intended for research and analytical applications. Octacosane is an endogenous metabolite with antibacterial activity. Octacosane shows high cytotoxicity against murine melanoma B16F10-Nex2 cells besides inducing protection against a grafted subcutaneous melanoma. Octacosane has the larvicidal activity against mosquito Culex quinquefasciatus with the LC50 concentration of 7.2 mg/l .
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Cat. No.: HY-N14349
CAS No.: 60696-52-8
Synonyms: ARQ; Asterriquinone SU5504
Asterriquinone (ARQ), a Asterriquinone analog, is a Grb-2 binding inhibitor. Asterriquinone inhibits the Grb-2 binding activity to tyrosine phosphorylated EGFR, with an IC50 of 8.37 μM. Asterriquinone is a HIV1 reverse transcriptase inhibitor with a Ki of 2.3 μM. Asterriquinone also inhibits Grb-7 and PLC-γ binding activities. .
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Cat. No.: HY-50934R
CAS No.: 112522-64-2
Synonyms: N-acetyldinaline (Standard); CI-994 (Standard); Goe-5549 (Standard)
Research Areas:  

Cancer

Tacedinaline (Standard) is the analytical standard of Tacedinaline. This product is intended for research and analytical applications. Tacedinaline (N-acetyldinaline) is an inhibitor of the histone deacetylase (HDAC) with IC50s of 0.9, 0.9, 1.2 μM for recombinant HDAC 1, 2 and 3 respectively.
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Cat. No.: HY-P85812

Host:  

Mouse

Application:  

IHC-P, WB, ICC/IF, ELISA

Reactivity:  

Human

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Cat. No.: HY-P85817
Synonyms: GLUL; GLNS; Glutamine synthetase; GS; Glutamate decarboxylase; Glutamate--ammonia ligase

Host:  

Mouse

Application:  

WB, ICC/IF, ELISA, IHC-P

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P85357
Synonyms: RSPO1; R-spondin-1; Roof plate-specific spondin-1; hRspo1

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human

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Cat. No.: HY-P85357A
Synonyms: RSPO1; R-spondin-1; Roof plate-specific spondin-1; hRspo1

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human

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Cat. No.: HY-P75021
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Influenza A H6N8 (A/mallard/Ohio/217/1998) Hemagglutinin / HA Protein (His)
Species:  
Source:  
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Cat. No.: HY-P74926
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Influenza A H6N8 (A/mallard/Ohio/217/1998) Hemagglutinin Protein (HA1 Subunit) (His)
Species:  
Source:  
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Cat. No.: HY-P87371
Synonyms: 5730568A12Rik antibody; AI551049 antibody; CCD51_HUMAN antibody; CCDC51 antibody; Coiled coil domain containing 51 antibody; Coiled-coil domain-containing protein 51 antibody; FLJ12436 antibody; RGD1311466 antibody

Host:  

Mouse

Application:  

WB, IHC-P

Reactivity:  

Human

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Cat. No.: HY-P85857
Synonyms: KAT7; HBO1; HBOa; MYST2; Histone acetyltransferase KAT7; Histone acetyltransferase binding to ORC1; Lysine acetyltransferase 7; MOZ; YBF2/SAS3, SAS2 and TIP60 protein 2; MYST-2

Host:  

Mouse

Application:  

WB, ICC/IF, ELISA

Reactivity:  

Human

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