RADX - RPA1 related single stranded DNA binding protein, X-linked Gene

Homo sapiens

Also known as CXorf57

Gene ID: 55086 | Gene type: protein coding

About RADX

This gene has 6 transcripts (splice variants) and 188 orthologues. Broad expression in adrenal (RPKM 4.5), ovary (RPKM 4.0) and 24 other tissues.

Summary

Enables single-stranded DNA binding activity. Involved in negative regulation of double-strand break repair via homologous recombination. Located in nuclear speck and replication fork. [provided by Alliance of Genome Resources, Apr 2022]

RADX Products(2)

mRNA	Protein	Name
NM_001184782.2	NP_001171711.1	RPA-related protein RADX isoform 2
NM_018015.6	NP_060485.4	RPA-related protein RADX isoform 1

Protein Preferred Names

Protein Names

RPA-related protein RADX

RPA-related and RAD51-antagonist, X-chromosome

Related Diseases

Diseases

Alias

Schimke Immunoosseous Dysplasia

Schimke Immuno-Osseous Dysplasia	SIOD
Immunoosseous Dysplasia, Schimke Type	Schimke Syndrome
Immunoosseous Dysplasia Schimke Type	Spondyloepiphyseal Dysplasia - Nephrotic Syndrome
Spondyloepiphyseal Dysplasia Nephrotic Syndrome	Spondyloepiphyseal Dysplasia-Nephrotic Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-13058B	(R)-ADX-47273	Modulator	99.00%	Unkown
HY-RS11616	RADX Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	RADX	RGD	RGD:1589413
Canis familiaris	RADX	VGNC	VGNC:52594
Mus musculus	RADX	MGD	MGI:2147848
Bos taurus	RADX	VGNC	VGNC:52760

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