2. Gene
  3. PPP1R10 - protein phosphatase 1 regulatory subunit 10 Gene

PPP1R10 - protein phosphatase 1 regulatory subunit 10 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as p99; FB19; R111; CAT53; PNUTS; PP1R10

Gene ID: 5514 | Gene type: protein coding

About PPP1R10

Cytogenetic location: 6p21.33 Genomic coordinates (GRCh38): 6:30,600,413-30,617,243 (from NCBI)

This gene has 7 transcripts (splice variants), 1 gene allele, 196 orthologues and 2 paralogues. Ubiquitous expression in thyroid (RPKM 17.1), adrenal (RPKM 16.4) and 25 other tissues.

Summary

This gene encodes a protein Phosphatase 1 binding protein. The encoded protein plays a role in many cellular processes including cell cycle progression, DNA repair and Apoptosis by regulating the activity of protein Phosphatase 1. This gene lies within the major histocompatibility complex class I region on chromosome 6, and alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]

PPP1R10 Products(2)

mRNA Protein Name
NM_001376195.1 NP_001363124.1 serine/threonine-protein phosphatase 1 regulatory subunit 10
NM_002714.4 NP_002705.2 serine/threonine-protein phosphatase 1 regulatory subunit 10

PPP1R10 Protein Structure

Med26

Med26: TFIIS helical bundle-like domain (94 - 144)

zf-CCCH

zf-CCCH: Zinc finger C-x8-C-x5-C-x3-H type (and similar) (909 - 932)

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  • 940 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein phosphatase 1 regulatory subunit 10

HLA-C associated transcript 53

Related Diseases

Diseases Alias
Adrenal Gland Pheochromocytoma

Pheochromocytoma
Hypermethioninemia Due To Adenosine Kinase Deficiency

Adk Hypermethioninemia

Hypermethioninemia Encephalopathy Due To Adenosine Kinase Deficiency

Hypermethioninemia Encephalopathy Due To Adk Deficiency

Mrt8

Mental Retardation, Autosomal Recessive 8, Formerly

Mrt8, Formerly

HMAKD

Mental Retardation, Autosomal Recessive 8
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10976 PPP1R10 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus PPP1R10 VGNC VGNC:33221
Rattus norvegicus PPP1R10 RGD RGD:620079
Mus musculus PPP1R10 MGD MGI:1289273
Canis familiaris PPP1R10 VGNC VGNC:44876
Macaca mulatta PPP1R10 VGNC VGNC:76367
Felis catus PPP1R10 VGNC VGNC:68999