KLHL11 - kelch like family member 11 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55175

About KLHL11

Cytogenetic location: 17q21.2 Genomic coordinates (GRCh38): 17:41,848,518-41,865,423 (from NCBI)

This gene has 1 transcript (splice variant), 250 orthologues and 11 paralogues. Broad expression in testis (RPKM 5.8), brain (RPKM 4.6) and 25 other tissues.

Summary

Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

KLHL11 Products (1)

mRNA Protein Name
NM_018143.3 NP_060613.1 kelch-like protein 11 precursor

KLHL11 Protein Structure

BTB

BTB: BTB/POZ domain (85 - 199)

BACK

BACK: BTB And C-terminal Kelch (205 - 307)

Kelch_1

Kelch_1: Kelch motif (398 - 439)

Kelch_1

Kelch_1: Kelch motif (443 - 486)

Kelch_1

Kelch_1: Kelch motif (601 - 648)

  • 0
  • 200
  • 400
  • 600
  • 708 a.a.
Protein Preferred Names Protein Names

kelch-like protein 11

KLHL11 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
KLHL11 Q9NVR0 POU6F2 Homo sapiens P78424
Y2H Array
32296183
Intra
KLHL11 Q9NVR0 POU6F2 Homo sapiens P78424
Y2H Prey Pooling
32296183
Intra
KLHL11 Q9NVR0 IHO1 Homo sapiens Q8IYA8
Y2H Prey Pooling
32296183
Intra
KLHL11 Q9NVR0 IHO1 Homo sapiens Q8IYA8
Y2H Array
32296183
Intra
KLHL11 Q9NVR0 UBQLN2 Homo sapiens Q9UHD9
Y2H Prey Pooling
32296183
Intra
KLHL11 Q9NVR0 UBQLN2 Homo sapiens Q9UHD9
Validated Y2H
32296183
Intra
KLHL11 Q9NVR0 UBQLN2 Homo sapiens Q9UHD9
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

KLHL11 Antibodies

Cat. No. Product Name Application Reactivity
HY-P84831 KLHL11 Antibody (YA4528) WB, ICC/IF, FC, ELISA Human
HY-P84831A KLHL11 Antibody (YA4528)(PBS only) WB, ICC/IF, FC, ELISA Human
HY-P84832 KLHL11 Antibody (YA4529) WB, IHC-P, ICC/IF, ELISA Human
HY-P84832A KLHL11 Antibody (YA4529)(PBS only) WB, IHC-P, ICC/IF, ELISA Human
HY-P85241 KLHL11 Antibody (YA4933) WB, IHC-P, ICC/IF Human

Related Diseases

Diseases Alias
Polyradiculopathy
Acquired Night Blindness
Cold-Induced Sweating Syndrome 3
Ulnar Nerve Lesion

  • Lesion Of Ulnar Nerve

  • Mononeuritis Ulnar Nerve

  • Tardy Ulnar Nerve Palsy
Spinal Cord Lymphoma

  • Lymphoma Of The Spinal Cord

  • Spinal Cord Cancer

  • Spine Lymphoma

  • Spinal Cord--Cancer
Internuclear Ophthalmoplegia

  • Ophthalmoplegia Internuclearis

  • Bielschowsky-Lutz-Cogan Syndrome

  • Ino - [Internuclear Ophthalmoplegia]

  • Lhermitte Syndrome

  • Mlf - [Medial Longitudinal Fasciculus] Syndrome

  • Internuclear Paralysis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07355 KLHL11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus KLHL11 RGD RGD:1306673
Bos taurus KLHL11 VGNC VGNC:55842
Macaca mulatta KLHL11 VGNC VGNC:74083
Canis familiaris KLHL11 VGNC VGNC:42447
Felis catus KLHL11 VGNC VGNC:99094
Mus musculus KLHL11 MGD MGI:2388648
Others KLHL11 NCBI