PEF1 - penta-EF-hand domain containing 1 Gene

Homo sapiens

Also known as ABP32; PEF1A

Gene ID: 553115 | Gene type: protein coding

About PEF1

Cytogenetic location: 1p35.2 Genomic coordinates (GRCh38): 1:31,629,866-31,644,876 (from NCBI)

This gene has 8 transcripts (splice variants), 214 orthologues and 20 paralogues. Ubiquitous expression in thyroid (RPKM 29.9), placenta (RPKM 14.6) and 25 other tissues.

Summary

This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. The encoded protein has been shown to form a heterodimer with the programmed cell death 6 gene product and may modulate its function in Ca(2+) signaling. Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 1.[provided by RefSeq, May 2010]

PEF1 Products(2)

mRNA	Protein	Name
NM_001359651.2	NP_001346580.1	peflin isoform 2
NM_012392.4	NP_036524.1	peflin isoform 1

PEF1 Protein Structure

EF-hand_7

0
100
200
284 a.a.

Protein Preferred Names

Protein Names

peflin

PEF protein with a long N-terminal hydrophobic domain

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10317	PEF1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	PEF1	VGNC	VGNC:64110
Mus musculus	PEF1	MGD	MGI:1915148
Rattus norvegicus	PEF1	RGD	RGD:1359536
Bos taurus	PEF1	VGNC	VGNC:32739
Canis familiaris	PEF1	VGNC	VGNC:44412