1. Gene
  2. DNAJA4 - DnaJ heat shock protein family (Hsp40) member A4 Gene

DNAJA4 - DnaJ heat shock protein family (Hsp40) member A4 Gene

Homo sapiens

Also known as MST104; MSTP104; PRO1472

Gene ID: 55466 | Gene type: protein coding

About DNAJA4

This gene has 12 transcripts (splice variants), 211 orthologues and 3 paralogues. Broad expression in heart (RPKM 43.9), testis (RPKM 33.4) and 23 other tissues.

Summary

Enables chaperone binding activity and unfolded protein binding activity. Involved in several processes, including negative regulation of endothelial cell migration; negative regulation of inclusion body assembly; and protein refolding. Located in cytosol and membrane. [provided by Alliance of Genome Resources, Apr 2022]

DNAJA4 Products(8)

mRNA Protein Name
NM_001130182.2 NP_001123654.1 dnaJ homolog subfamily A member 4 isoform 2
NM_001130183.2 NP_001123655.1 dnaJ homolog subfamily A member 4 isoform 3
NM_001387384.1 NP_001374313.1 dnaJ homolog subfamily A member 4 isoform 4
NM_001387385.1 NP_001374314.1 dnaJ homolog subfamily A member 4 isoform 2
NM_001387386.1 NP_001374315.1 dnaJ homolog subfamily A member 4 isoform 5
NM_001387387.1 NP_001374316.1 dnaJ homolog subfamily A member 4 isoform 6
NM_001387388.1 NP_001374317.1 dnaJ homolog subfamily A member 4 isoform 2
NM_018602.4 NP_061072.3 dnaJ homolog subfamily A member 4 isoform 1

DNAJA4 Protein Structure

DnaJ

DnaJ: DnaJ domain (7 - 65)

DnaJ_CXXCXGXG

DnaJ_CXXCXGXG: DnaJ central domain (135 - 201)

DnaJ_C

DnaJ_C: DnaJ C terminal domain (258 - 332)

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  • 300
  • 397 a.a.
Protein Preferred Names Protein Names

dnaJ homolog subfamily A member 4

DnaJ (Hsp40) homolog, subfamily A, member 4

Related Diseases

Diseases Alias
Plantar Wart

Verruca Plantaris

Verrucae On Sole Of Foot

Mosaic Plantar Warts

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus DNAJA4 RGD RGD:1310035
Macaca mulatta DNAJA4 VGNC VGNC:84334
Bos taurus DNAJA4 VGNC VGNC:53935
Mus musculus DNAJA4 MGD MGI:1927638
Felis catus DNAJA4 VGNC VGNC:80985
Canis familiaris DNAJA4 VGNC VGNC:59071