SVOP - SV2 related protein Gene

Homo sapiens

Also known as SLC22B4

Gene ID: 55530 | Gene type: protein coding

About SVOP

Cytogenetic location: 12q24.11 Genomic coordinates (GRCh38): 12:108,907,741-109,021,068 (from NCBI)

This gene has 5 transcripts (splice variants), 206 orthologues and 22 paralogues. Biased expression in brain (RPKM 14.1) and adrenal (RPKM 0.9).

Summary

Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in synaptic vesicle. [provided by Alliance of Genome Resources, Apr 2022]

SVOP Products(1)

mRNA	Protein	Name
NM_018711.5	NP_061181.1	synaptic vesicle 2-related protein

SVOP Protein Structure

Sugar_tr

MFS_1

0
100
200
300
400
483 a.a.

Protein Preferred Names

Protein Names

synaptic vesicle 2-related protein

SV2 related protein homolog

Related Diseases

Diseases

Alias

Developmental And Epileptic Encephalopathy 4

DEE4	Epileptic Encephalopathy, Early Infantile, 4
Eiee4	Early Infantile Epileptic Encephalopathy 4
Stxbp1-Related Early-Onset Encephalopathy	Early Myoclonic Encephalopathy
Developmental And Epileptic Encephalopathy, 4	Stxbp1 Disorders
Stxbp1 Encephalopathy	Developmental And Epileptic Encephalopathy, Type 4
Early-Infantile Epileptic Encephalopathy 4	Stxbp1 Encephalopathy With Epilepsy
Stxbp1 Epileptic Encephalopathy	Stxbp1-Related Developmental And Epileptic Encephalopathy
Stxbp1-Related Epileptic Encephalopathy	Eme
Neonatal Epilepsy With Suppression-Burst Pattern	Encephalopathy, Epileptic, Early Infantile, Type 4

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14061	SVOP Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SVOP	MGD	MGI:1915916
Canis familiaris	SVOP	VGNC	VGNC:47008
Felis catus	SVOP	VGNC	VGNC:65865
Rattus norvegicus	SVOP	RGD	RGD:620277
Macaca mulatta	SVOP	VGNC	VGNC:78208
Bos taurus	SVOP	VGNC	VGNC:35498