UTP6 - UTP6 small subunit processome component Gene

Also Known as HCA66; C17orf40

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55813

About UTP6

This gene has 9 transcripts (splice variants) and 216 orthologues. Ubiquitous expression in lymph node (RPKM 15.1), testis (RPKM 14.9) and 25 other tissues.

Summary

Predicted to enable snoRNA binding activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in chromosome and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

UTP6 Products (1)

mRNA Protein Name
NM_018428.3 NP_060898.2 U3 small nucleolar RNA-associated protein 6 homolog

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
Biological Process GO Annotation Evidence References Source
involved in ribosomal small subunit biogenesis IDA
IDA: Inferred from direct assay
34516797 GOA
Cellular Component GO Annotation Evidence References Source
part of small-subunit processome IDA
IDA: Inferred from direct assay
34516797 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

UTP6 Protein Structure

U3_assoc_6

U3_assoc_6: U3 small nucleolar RNA-associated protein 6 (9 - 92)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 597 a.a.
Protein Preferred Names Protein Names

U3 small nucleolar RNA-associated protein 6 homolog

  • UTP6, small subunit (SSU) processome component, homolog

UTP6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
UTP6 Q9NYH9 APOE Homo sapiens P02649
Validated Y2H
32814053
Intra
UTP6 Q9NYH9 APOE Homo sapiens P02649
Y2H Array
32814053
Intra
UTP6 Q9NYH9 APOE Homo sapiens P02649
Y2H Pooling
32814053
Intra
UTP6 Q9NYH9 GBP1 Homo sapiens P32455
Anti Tag CoIP
28514442
Intra
UTP6 Q9NYH9 GBP1 Homo sapiens P32455
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Chromosome 17q11.2 Deletion Syndrome

  • Nf1 Microdeletion Syndrome

  • 17q11 Microdeletion Syndrome

  • Neurofibromatosis Type 1 Microdeletion Syndrome

  • Van Asperen Syndrome

  • Del(17)(Q11)

  • Monosomy 17q11

  • Chromosome 17q11.2 Deletion Syndrome, 1.4mb
Interstitial Keratitis
Bladder Squamous Cell Carcinoma

  • Squamous Cell Carcinoma Of Bladder

  • Epidermoid Carcinoma Of The Urinary Bladder

  • Carcinoma Squamous Cell Bladder
Chromosome 15q26-Qter Deletion Syndrome

  • Drayer Syndrome

  • 15q26 Deletion Syndrome

  • Distal 15q Deletion Syndrome

  • Distal Monosomy 15q

  • Telomeric 15q Deletion Syndrome

  • Monosomy 15q26
Congenital Syphilis

  • Syphilis, Congenital

  • Congenital Syphilis, Unspecified

  • Mtct Of Syphilis

  • Mother-To-Child Transmission Of Syphilis

  • Syphilis Congenital

  • Hereditary Syphilis

  • Heredosyphilis
Hepatocellular Carcinoma

  • Liver Cancer

  • Primary Liver Cancer

  • HCC

  • Hepatoma

  • Malignant Neoplasm Of Liver

  • Liver Neoplasms

  • Cancer, Hepatocellular

  • Liver Cell Carcinoma

  • Lcc

  • Hepatoblastoma, Somatic

  • Hepatic Cancer

  • Primary Malignant Neoplasm Of Liver

  • Rare Tumor Of Liver And Intrahepatic Biliary Tract

  • Hepatocellular Carcinoma, Somatic

  • Hepatocellular Carcinoma, Childhood Type, Somatic

  • Hepatocellular Cancer, Somatic

  • Ca Liver - Primary

  • Hepatic Neoplasm

  • Malignant Hepato-Biliary Neoplasm

  • Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

  • Malignant Neoplasm Of Liver, Primary

  • Malignant Tumor Of Liver

  • Neoplasm Of Liver

  • Non-Resectable Primary Hepatic Malignant Neoplasm

  • Resectable Malignant Neoplasm Of Liver

  • Resectable Malignant Neoplasm Of The Liver

  • Primary Liver Carcinoma

  • Primary Malignant Liver Neoplasm

  • Primary Cancer Of Liver

  • Primary Tumor Of The Liver

  • Rare Tumor Of Liver And Ibt

  • Hepatocellular Cancer

  • Neoplasm Of The Liver

  • Carcinoma, Hepatocellular

  • Hepatomas

  • Liver Neoplasm

  • Liver Carcinoma

  • Liver And Intrahepatic Biliary Tract Carcinoma

  • Malignant Hepatobiliary Neoplasm

  • Adult Primary Hepatocellular Carcinoma

  • Hepatoblastoma

  • Carcinoma Of Liver

  • Malignant Liver Tumour

  • Malignant Hepatic Tumour
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15581 UTP6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus UTP6 MGD MGI:2445193
Canis familiaris UTP6 VGNC VGNC:48214
Rattus norvegicus UTP6 RGD RGD:1311017
Felis catus UTP6 VGNC VGNC:66908
Macaca mulatta UTP6 VGNC VGNC:79122
Bos taurus UTP6 VGNC VGNC:36748
Others UTP6 NCBI