SUSD2 - sushi domain containing 2 Gene

Homo sapiens

Also known as W5C5; BK65A6.2

Gene ID: 56241 | Gene type: protein coding

About SUSD2

Cytogenetic location: 22q11.23 Genomic coordinates (GRCh38): 22:24,181,487-24,189,106 (from NCBI)

This gene has 2 transcripts (splice variants), 239 orthologues and 2 paralogues. Biased expression in lung (RPKM 80.9), kidney (RPKM 36.6) and 4 other tissues.

Summary

Involved in negative regulation of cell cycle G1/S phase transition and negative regulation of cell division. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SUSD2 Products(1)

mRNA	Protein	Name
NM_019601.4	NP_062547.1	sushi domain-containing protein 2 precursor

SUSD2 Protein Structure

Somatomedin_B

AMOP

VWD

Sushi

0
200
400
600
822 a.a.

Protein Preferred Names

Protein Names

sushi domain-containing protein 2

Sushi domain (SCR repeat) containing

Related Diseases

Diseases

Alias

Adhesions Of Uterus

Intrauterine Adhesions	Intrauterine Synechiae
Band Of Uterus	Asherman Syndrome
Internal Adhesion Of Uterus	Internal Band Of Uterus

Breast Cancer

Breast Carcinoma	Male Breast Cancer
Breast Cancer, Familial	Malignant Neoplasm Of Breast
Breast Cancer, Susceptibility To	Breast Cancer, Early-Onset
Malignant Tumor Of Breast	Carcinoma Of Male Breast
Breast Cancer, Invasive Ductal	Breast Cancer, Protection Against
Breast Cancer, Somatic	Breast Cancer, Male
Breast Cancer, Lobular, Somatic	Breast Tumor
Mammary Cancer	Mammary Tumor
Malignant Neoplasm Of Male Breast	Mammary Carcinoma
Male Breast Carcinoma	Familial Cancer Of Breast
Invasive Ductal Breast Carcinoma	Breast Cancer Susceptibility
Breast Cancer, Male, Susceptibility To	Breast Cancer, Early-Onset, Susceptibility To
Malignant Tumor Of The Breast	Mammary Neoplasm
Primary Breast Cancer	Neoplasm Of Male Breast
Carcinoma Of Breast	Breast Cancer In Men
Familial Breast Cancer	Cancer Of Breast
BC	Breast Cancer Familial
Breast Cancer Familial Male	Breast Cancer, Familial Male
Breast Male Carcinoma	Breast Neoplasms
Breast Neoplasms, Male	Mammary Tumors
Mammary Carcinomas	Cancer, Breast
Cancer, Breast, Susceptibility	Invasive Breast Ductal Carcinoma
Breast Neoplasm	Susceptibility To Breast Cancer
Mammary Neoplasms	Animal Mammary Neoplasms
Primary Malignant Neoplasm Of Breast	Infiltrating Ductal Carcinoma Of Breast
Infiltrating Duct Carcinoma Of Unspecified Site	Infiltrating Ductular Carcinoma Of Unspecified Site
Invasive Breast Carcinoma Of No Special Type	Microinvasive Carcinoma Of Breast
Carcinoma With Apocrine Differentiation

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14047	SUSD2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SUSD2	VGNC	VGNC:78251
Canis familiaris	SUSD2	VGNC	VGNC:46998
Rattus norvegicus	SUSD2	RGD	RGD:1308595
Mus musculus	SUSD2	MGD	MGI:1918983
Felis catus	SUSD2	VGNC	VGNC:65854
Bos taurus	SUSD2	VGNC	VGNC:35487

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