SUSD2 - sushi domain containing 2 Gene

Also Known as W5C5; BK65A6.2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 56241

About SUSD2

Cytogenetic location: 22q11.23 Genomic coordinates (GRCh38): 22:24,181,487-24,189,106 (from NCBI)

This gene has 2 transcripts (splice variants), 239 orthologues and 2 paralogues. Biased expression in lung (RPKM 80.9), kidney (RPKM 36.6) and 4 other tissues.

Summary

Involved in negative regulation of cell cycle G1/S phase transition and negative regulation of cell division. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SUSD2 Products (1)

mRNA Protein Name
NM_019601.4 NP_062547.1 sushi domain-containing protein 2 precursor

SUSD2 Protein Structure

Somatomedin_B

Somatomedin_B: Somatomedin B domain (28 - 64)

AMOP

AMOP: AMOP domain (288 - 433)

VWD

VWD: von Willebrand factor type D domain (448 - 612)

Sushi

Sushi: Sushi repeat (SCR repeat) (730 - 778)

  • 0
  • 200
  • 400
  • 600
  • 822 a.a.
Protein Preferred Names Protein Names

sushi domain-containing protein 2

  • Sushi domain (SCR repeat) containing

SUSD2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SUSD2 Q9UGT4 KRTAP10-8 Homo sapiens P60410
Y2H Array
32296183
Intra
SUSD2 Q9UGT4 KRTAP10-8 Homo sapiens P60410
Y2H Prey Pooling
32296183
Intra
SUSD2 Q9UGT4 TNS2 Homo sapiens Q63HR2
Y2H Array
32296183
Intra
SUSD2 Q9UGT4 TNS2 Homo sapiens Q63HR2
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Adhesions Of Uterus

  • Intrauterine Adhesions

  • Intrauterine Synechiae

  • Band Of Uterus

  • Asherman Syndrome

  • Internal Adhesion Of Uterus

  • Internal Band Of Uterus
Breast Cancer

  • Breast Carcinoma

  • Male Breast Cancer

  • Breast Cancer, Familial

  • Malignant Neoplasm Of Breast

  • Breast Cancer, Susceptibility To

  • Breast Cancer, Early-Onset

  • Malignant Tumor Of Breast

  • Carcinoma Of Male Breast

  • Breast Cancer, Invasive Ductal

  • Breast Cancer, Protection Against

  • Breast Cancer, Somatic

  • Breast Cancer, Male

  • Breast Cancer, Lobular, Somatic

  • Breast Tumor

  • Mammary Cancer

  • Mammary Tumor

  • Malignant Neoplasm Of Male Breast

  • Mammary Carcinoma

  • Male Breast Carcinoma

  • Familial Cancer Of Breast

  • Invasive Ductal Breast Carcinoma

  • Breast Cancer Susceptibility

  • Breast Cancer, Male, Susceptibility To

  • Breast Cancer, Early-Onset, Susceptibility To

  • Malignant Tumor Of The Breast

  • Mammary Neoplasm

  • Primary Breast Cancer

  • Neoplasm Of Male Breast

  • Carcinoma Of Breast

  • Breast Cancer In Men

  • Familial Breast Cancer

  • Cancer Of Breast

  • BC

  • Breast Cancer Familial

  • Breast Cancer Familial Male

  • Breast Cancer, Familial Male

  • Breast Male Carcinoma

  • Breast Neoplasms

  • Breast Neoplasms, Male

  • Mammary Tumors

  • Mammary Carcinomas

  • Cancer, Breast

  • Cancer, Breast, Susceptibility

  • Invasive Breast Ductal Carcinoma

  • Breast Neoplasm

  • Susceptibility To Breast Cancer

  • Mammary Neoplasms

  • Animal Mammary Neoplasms

  • Primary Malignant Neoplasm Of Breast

  • Infiltrating Ductal Carcinoma Of Breast

  • Infiltrating Duct Carcinoma Of Unspecified Site

  • Infiltrating Ductular Carcinoma Of Unspecified Site

  • Invasive Breast Carcinoma Of No Special Type

  • Microinvasive Carcinoma Of Breast

  • Carcinoma With Apocrine Differentiation
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14047 SUSD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21774 Susd2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28291 Susd2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta SUSD2 VGNC VGNC:78251
Canis familiaris SUSD2 VGNC VGNC:46998
Rattus norvegicus SUSD2 RGD RGD:1308595
Mus musculus SUSD2 MGD MGI:1918983
Felis catus SUSD2 VGNC VGNC:65854
Bos taurus SUSD2 VGNC VGNC:35487
Others SUSD2 NCBI