YLPM1 - YLP motif containing 1 Gene

Also Known as ZAP3; ZAP113; PPP1R169; C14orf170

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 56252

About YLPM1

Cytogenetic location: 14q24.3 Genomic coordinates (GRCh38): 14:74,763,316-74,837,318 (from NCBI)

This gene has 9 transcripts (splice variants) and 210 orthologues. Ubiquitous expression in testis (RPKM 14.0), brain (RPKM 9.5) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in regulation of telomere maintenance. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Located in cytosol and nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

YLPM1 Products (2)

mRNA Protein Name
NM_001411052.1 NP_001397981.1 YLP motif-containing protein 1 isoform 2
NM_019589.3 NP_062535.2 YLP motif-containing protein 1 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21078624 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
17890166 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

YLPM1 Protein Structure

AAA_33

AAA_33: AAA domain (1836 - 1976)

  • 0
  • 400
  • 800
  • 1200
  • 1600
  • 2000
  • 2146 a.a.
Protein Preferred Names Protein Names

YLP motif-containing protein 1

  • nuclear protein ZAP3

YLPM1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
YLPM1 P49750 CACNA1A Homo sapiens O00555
Y2H
21078624
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Ceroid Lipofuscinosis, Neuronal, 6a

  • Neuronal Ceroid Lipofuscinosis 6

  • CLN6

  • Vlincl

  • Cln6 Disease

  • Ceroid Lipofuscinosis, Neuronal, 6

  • Late-Infantile Neuronal Ceroid Lipofuscinosis

  • CLN6A

  • Neuronal Ceroid Lipofuscinosis, Late Infantile, Variant

  • Neuronal Ceroid Lipofuscinosis 6a

  • Neuronal Ceroid Lipofuscinosis 6 Variable Age Of Onset

  • Cln6 Disease, Adult Kufs Type A

  • Cln6 Disease, Late Infantile

  • Neuronal Ceroid Lipofuscinosis, Gypsy/Indian Early Juvenile Variant

  • Ceroid Lipofuscinosis Neuronal 6

  • Cln6-Related Neuronal Ceroid Lipofuscinosis

  • Late Infantile Neuronal Ceroid Lipofuscinosis

  • Jansky-Bielschowsky Disease

  • Lincl

  • Late Infantile Ncl

  • Neuronal Ceroid Lipofuscinosis 6 With Variable Age At Onset

  • Variant Late-Onset Infantile Neuronal Ceroid Lipofuscinosis

  • Ceroid Lipofuscinosis, Neuronal, Late Infantile, Variant

  • Lipofuscinosis, Ceroid, Neuronal, Type 6

  • Ceroid Lipofuscinosis, Neuronal, 5
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15928 YLPM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus YLPM1 VGNC VGNC:37031
Mus musculus YLPM1 MGD MGI:1926195
Canis familiaris YLPM1 VGNC VGNC:48494
Macaca mulatta YLPM1 VGNC VGNC:79092
Rattus norvegicus YLPM1 RGD RGD:1564946
Others YLPM1 NCBI