Fgf21 - fibroblast growth factor 21 Gene

Also Known as Fgf8c

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56636

Summary

Predicted to enable Fibroblast Growth Factor receptor binding activity and growth factor activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within positive regulation of MAPKKK cascade by Fibroblast Growth Factor receptor signaling pathway and positive regulation of cell population proliferation. Located in extracellular space. Is expressed in several structures, including alimentary system; cerebellum; integumental system; limb; and skeleton. Orthologous to human FGF21 (Fibroblast Growth Factor 21). [provided by Alliance of Genome Resources, Apr 2022]

Fgf21 Products (1)

mRNA Protein Name
NM_020013.4 NP_064397.1 fibroblast growth factor 21 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway IGI
IGI: Inferred from genetic interaction
18187602 MGI
acts upstream of or within positive regulation of cell population proliferation IGI
IGI: Inferred from genetic interaction
18187602 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: Inferred from mutant phenotype
22302939 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
30605666 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibroblast growth factor 21

  • fibroblast growth factor 8c

Recombinant Fgf21 Proteins

Cat. No. Product Name Accession Purity
HY-P7173 FGF-21 Protein, Mouse Q9JJN1 (A29-S210) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P72651 FGF-21 Protein, Mouse (HEK293, His) Q9JJN1 (A29-S210) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P11881 IUB288 Activator / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgf21 NCBI NCBI:26291