KIF15 - kinesin family member 15 Gene

Also Known as KLP2; HKLP2; KNSL7; BRDCS2; NY-BR-62

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 56992

About KIF15

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:44,761,794-44,868,687 (from NCBI)

This gene has 7 transcripts (splice variants), 1 gene allele, 198 orthologues, 41 paralogues and is associated with 1 phenotype. Biased expression in testis (RPKM 8.0), bone marrow (RPKM 4.1) and 13 other tissues.

Summary

Predicted to enable microtubule binding activity and microtubule motor activity. Predicted to be involved in microtubule-based movement. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

KIF15 Products (1)

mRNA Protein Name
NM_020242.3 NP_064627.1 kinesin-like protein KIF15

KIF15 Protein Structure

Kinesin

Kinesin: Kinesin motor domain (32 - 363)

(463 - 551)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1388 a.a.
Protein Preferred Names Protein Names

kinesin-like protein KIF15

  • kinesin-like 7

KIF15 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
KIF15 Q9NS87 MKI67 Homo sapiens P46013
Pull Down
10878014
Cross: Cross-species interaction Intra: Intraspecies interaction

KIF15 Antibodies

Cat. No. Product Name Application Reactivity
HY-P89571 KIF15 Antibody (YA8915) WB, IP, ELISA human

Related Diseases

Diseases Alias
Braddock-Carey Syndrome 2

  • BRDCS2
21q22.11q22.12 Microdeletion Syndrome

  • Del(21)(Q22.11q22.12)

  • Monosomy 21q22.11q22.12
Goldberg-Shprintzen Syndrome

  • Goldberg-Shprintzen Megacolon Syndrome

  • GOSHS

  • Megacolon-Microcephaly Syndrome
Breast Cancer

  • Breast Carcinoma

  • Male Breast Cancer

  • Breast Cancer, Familial

  • Malignant Neoplasm Of Breast

  • Breast Cancer, Susceptibility To

  • Breast Cancer, Early-Onset

  • Malignant Tumor Of Breast

  • Carcinoma Of Male Breast

  • Breast Cancer, Invasive Ductal

  • Breast Cancer, Protection Against

  • Breast Cancer, Somatic

  • Breast Cancer, Male

  • Breast Cancer, Lobular, Somatic

  • Breast Tumor

  • Mammary Cancer

  • Mammary Tumor

  • Malignant Neoplasm Of Male Breast

  • Mammary Carcinoma

  • Male Breast Carcinoma

  • Familial Cancer Of Breast

  • Invasive Ductal Breast Carcinoma

  • Breast Cancer Susceptibility

  • Breast Cancer, Male, Susceptibility To

  • Breast Cancer, Early-Onset, Susceptibility To

  • Malignant Tumor Of The Breast

  • Mammary Neoplasm

  • Primary Breast Cancer

  • Neoplasm Of Male Breast

  • Carcinoma Of Breast

  • Breast Cancer In Men

  • Familial Breast Cancer

  • Cancer Of Breast

  • BC

  • Breast Cancer Familial

  • Breast Cancer Familial Male

  • Breast Cancer, Familial Male

  • Breast Male Carcinoma

  • Breast Neoplasms

  • Breast Neoplasms, Male

  • Mammary Tumors

  • Mammary Carcinomas

  • Cancer, Breast

  • Cancer, Breast, Susceptibility

  • Invasive Breast Ductal Carcinoma

  • Breast Neoplasm

  • Susceptibility To Breast Cancer

  • Mammary Neoplasms

  • Animal Mammary Neoplasms

  • Primary Malignant Neoplasm Of Breast

  • Infiltrating Ductal Carcinoma Of Breast

  • Infiltrating Duct Carcinoma Of Unspecified Site

  • Infiltrating Ductular Carcinoma Of Unspecified Site

  • Invasive Breast Carcinoma Of No Special Type

  • Microinvasive Carcinoma Of Breast

  • Carcinoma With Apocrine Differentiation
Gastric Cancer

  • Stomach Cancer

  • Gastric Carcinoma

  • Stomach Carcinoma

  • Gastric Cancer, Somatic

  • Gastric Neoplasm

  • Carcinoma Of Stomach

  • Stomach Neoplasms

  • Malignant Neoplasm Of Stomach

  • Gastric Cancer Risk After H. Pylori Infection

  • Cancer Of The Stomach

  • Adult Stomach Cancer

  • Adult Stomach Carcinoma

  • GASC

  • Gastric Cancer Intestinal

  • Gastric Cancers

  • Gastric Carcinomas

  • Cancer, Gastric

  • Stomach Neoplasm

  • Malignant Neoplasm Of Body Of Stomach

  • Malignant Tumor Of Lesser Curve Of Stomach

  • Gastrocarcinoma Of Unspecified Site

  • Leather Bottle Stomach

  • Carcinoma Of Fundus Of Stomach

  • Cancer Of Fundus Of Stomach

  • Primary Malignant Neoplasm Of Body Of Stomach

  • Cancer Of Body Of Stomach

  • Primary Malignant Neoplasm Of Pyloric Antrum

  • Pyloric Antrum Cancer

  • Malignant Tumour Of Stomach
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15948 Kif15-IN-1 Inhibitor 99.63% Unkown
HY-115570 GW406108X Inhibitor 98.0% Unkown
HY-15949 Kif15-IN-2 Inhibitor 98.38% Unkown
HY-115570A (Z/E)-GW406108X Inhibitor / Unkown
HY-175496 Acid Ceramidase-IN-3 Inhibitor / Unkown
HY-RS07264 KIF15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19702 Kif15 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26197 Kif15 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris KIF15 VGNC VGNC:42384
Mus musculus KIF15 MGD MGI:1098258
Macaca mulatta KIF15 VGNC VGNC:73844
Bos taurus KIF15 VGNC VGNC:30584
Rattus norvegicus KIF15 RGD RGD:727790
Felis catus KIF15 VGNC VGNC:63104
Others KIF15 NCBI