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57179

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By Targets:	5-HT Receptor (1) CaMK (2) LPL Receptor (1) Parasite (2)
By Research Areas:	Infection (2) Inflammation/Immunology (1) Neurological Disease (1)

Inhibitors & Agonists

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-117684

Cabamiquine 1 Publications Verification DDD107498; DDD-498; M5717	Parasite CaMK	Infection
Cabamiquine (DDD107498) is a potent and orally active antimalarial agent, inhibits multiple life-cycle stages of the parasite, with an EC₅₀ of 1 nM against P. falciparum 3D7. Cabamiquine inhibits protein synthesis by targeting eEF2/CaMKIII, with an EC₅₀ of 2 nM for WT-PfeEF2 .

HY-116146

CYM50179 1 Publications Verification	LPL Receptor	Inflammation/Immunology
CYM50179 (compound 22n) is a potent and selective S1P4-R (Sphingosine-1-phosphate4 receptor) agonist with an EC₅₀ of 46 nM .

HY-117684A

Cabamiquine succinate 1 Publications Verification DDD107498 succinate; DDD-498 succinate; M5717 succinate	Parasite CaMK	Infection
Cabamiquine (DDD107498) succinate is a potent and orally active antimalarial agent, inhibits multiple life-cycle stages of the parasite, with an EC₅₀ of 1 nM against P. falciparum 3D7. Cabamiquine succinate inhibits protein synthesis by targeting eEF2/CaMKIII, with an EC₅₀ of 2 nM for WT-PfeEF2 .

HY-176910

IHCH-7179	5-HT Receptor	Neurological Disease
IHCH-7179 is a 5-HT receptor modulator. IHCH-7179 can antagonize 5-HT_2A receptor and activate 5-HT_1A receptor. IHCH-7179 can be used for the research of neurological disease .

Host:	Mouse (3) Rabbit (2)
Reactivity:	Human (5) Rat (2) Mouse (4) Monkey (1)
Application:	IHC-P (3) ICC/IF (2) IP (2) IHC-F (1) WB (3) FC (1) ELISA (3)
Isotype:	IgG (2) IgG2a (1) IgG2b (1)
Conjugation:	Non-conjugated (5)
Clonality:	Monoclonal (4) Recombinant (1)
Modification:	Phosphorylated (1) Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86027

	Cadherin Antibody (YA5719)	IHC-P, ELISA	Human, Mouse, Rat
	Cadherin Antibody (YA5719) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Cadherin.

HY-P87492

	RanBP3 Antibody (YA7179)	WB, IHC-P, IHC-F, ICC/IF, FC, IP	Human
	RanBP3 Antibody (YA7179) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RanBP3.

HY-P86087

	Phospho-beta Catenin(Ser675) Antibody (YA5779) CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Phospho-beta Catenin(Ser675) Antibody (YA5779) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-beta Catenin(Ser675).

HY-P86025

	Oct-2 Antibody (YA5717) POU domain, class 2, transcription factor 2; Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Octamer-binding protein 2; Oct-2; Octamer-binding transcription factor 2; OTF-2;	IHC-P, ELISA	Human, Mouse
	Oct-2 Antibody (YA5717) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Oct-2.

HY-P85487

	Transcription Initiation Factor IIB Antibody (YA5179) General transcription factor IIB; General transcription factor TFIIB; gtf2b; RNA polymerase II transcription factor IIB; S300 II; S300-II; TF IIB; TF2B; TF2B_HUMAN; TFIIB; Transcription initiation factor IIB.	WB	Human, Mouse, Monkey
	Transcription Initiation Factor IIB Antibody (YA5179) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Transcription Initiation Factor IIB.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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