2. Gene
  3. EP400 - E1A binding protein p400 Gene

EP400 - E1A binding protein p400 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as P400; CAGH32; TNRC12

Gene ID: 57634 | Gene type: protein coding

About EP400

Cytogenetic location: 12q24.33 Genomic coordinates (GRCh38): 12:131,949,942-132,080,460 (from NCBI)

This gene has 9 transcripts (splice variants), 229 orthologues and 30 paralogues. Ubiquitous expression in testis (RPKM 8.1), ovary (RPKM 5.8) and 25 other tissues.

Summary

Predicted to enable several functions, including ATP binding activity; ATP-dependent chromatin remodeler activity; and protein antigen binding activity. Involved in histone H2A acetylation and histone H4 acetylation. Part of NuA4 Histone Acetyltransferase complex and Swr1 complex. [provided by Alliance of Genome Resources, Apr 2022]

EP400 Products(1)

mRNA Protein Name
NM_015409.5 NP_056224.3 E1A-binding protein p400

EP400 Protein Structure

HSA

HSA: HSA (764 - 835)

SNF2_N

SNF2_N: SNF2 family N-terminal domain (1058 - 1338)

Helicase_C

Helicase_C: Helicase conserved C-terminal domain (1897 - 1963)

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  • 3123 a.a.
Protein Preferred Names Protein Names

E1A-binding protein p400

CAG repeat protein 32

Related Diseases

Diseases Alias
Ossifying Fibromyxoid Tumor

Ossifying Fibromyxoid Tumour

Ossifying Fibromyxoma
Endometrial Stromal Sarcoma

Ess

Endometrial Stromal Sarcoma, High Grade

Undifferentiated Endometrial Sarcoma

Stromal Sarcoma Of The Corpus Uteri

Sarcoma Endometrial Stromal

Sarcoma, Endometrial Stromal

Undifferentiated Stromal Sarcoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04408 EP400 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta EP400 VGNC VGNC:97765
Mus musculus EP400 MGD MGI:1276124
Canis familiaris EP400 VGNC VGNC:40390
Bos taurus EP400 VGNC VGNC:28517
Rattus norvegicus EP400 RGD RGD:1304733