DDX55 - DEAD-box helicase 55 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57696

About DDX55

This gene has 13 transcripts (splice variants), 206 orthologues and 38 paralogues. Ubiquitous expression in lymph node (RPKM 4.3), bone marrow (RPKM 4.0) and 25 other tissues.

Summary

This gene encodes a member of protein family containing a characteristic Asp-Glu-Ala-Asp (DEAD) motif. These proteins are putative RNA helicases, and may be involved in a range of nuclear processes including translational initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Multiple alternatively spliced transcript variants have been found for this gene. Pseudogenes have been identified on chromosomes 1 and 12. [provided by RefSeq, Feb 2016]

DDX55 Products (1)

mRNA Protein Name
NM_020936.3 NP_065987.1 ATP-dependent RNA helicase DDX55

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DDX55 Protein Structure

DEAD

DEAD: DEAD/DEAH box helicase (33 - 212)

Helicase_C

Helicase_C: Helicase conserved C-terminal domain (292 - 363)

DUF4217

DUF4217: Domain of unknown function (DUF4217) (403 - 465)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 600 a.a.
Protein Preferred Names Protein Names

ATP-dependent RNA helicase DDX55

  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 55

DDX55 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
DDX55 Q8NHQ9 KRTAP10-8 Homo sapiens P60410
Y2H Array
25416956
Intra
DDX55 Q8NHQ9 KRTAP10-8 Homo sapiens P60410
Y2H Prey Pooling
25416956
Intra
DDX55 Q8NHQ9 AGTRAP Homo sapiens Q6RW13
Validated Y2H
25416956
Intra
DDX55 Q8NHQ9 AGTRAP Homo sapiens Q6RW13
Y2H Prey Pooling
25416956
Intra
DDX55 Q8NHQ9 AGTRAP Homo sapiens Q6RW13
Y2H Array
25416956
Intra
DDX55 Q8NHQ9 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra
DDX55 Q8NHQ9 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Intra
DDX55 Q8NHQ9 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Atrial Septal Defect 1

  • ASD1

  • Atrial Heart Septal Defect 1

  • Asd
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03660 DDX55 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus DDX55 VGNC VGNC:27977
Macaca mulatta DDX55 VGNC VGNC:71681
Felis catus DDX55 VGNC VGNC:61416
Mus musculus DDX55 MGD MGI:1915098
Rattus norvegicus DDX55 RGD RGD:2324094
Canis familiaris DDX55 VGNC VGNC:39865
Others DDX55 NCBI