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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
57700
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "57700" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: PEG-PPG-PEG, 7700 (Average Mn)
Cat. No.: HY-P9949
CAS No.: 241473-69-8
Synonyms: Sch 55700; CDP-835; JES1-39D10
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Synonyms: AVE8062; AC7700
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Ombrabulin (AVE8062) is a derivative of CA-4 phosphate, which is known to exhibit antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells.
Cat. No.: HY-18256
CAS No.: 253426-24-3
Synonyms: AVE8062 hydrochloride; AC7700 hydrochloride
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Ombrabulin hydrochloride is a derivative of CA-4 phosphate, which is known to exhibit antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells.
Cat. No.: HY-131629
CAS No.: 67579-73-1
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N-Desmethyl-U-47700 is the primary metabolite of U-47700 (an opioid agonist) .
Cat. No.: HY-116881
CAS No.: 221660-80-6
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SCH 57790 is a selective antegonist for muscarinic M2 receptor, which increases acetylcholine release, and thus improves cognitive performance. SCH 57790 reverses Scopolamine (HY-N0296)-induced memory deficits in mice, without significant toxicity (100 mg/kg).
Cat. No.: HY-123681
CAS No.: 98164-11-5
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R 57720 is an antiepileptic agent that exhibits dose-dependent anticonvulsant activity across multiple postnatal rat age groups. R 57720 inhibits severe generalized tonic-clonic seizures induced by Pentylenetetrazol. R 57720 can be used for epilepsy research .
Cat. No.: HY-176106
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1-Naphthyl U-47700 is an α-isomer. 1-Naphthyl U-47700 is a racemic mixtures of the trans-isomers [R,R and S,S]. 1-Naphthyl U-47700 activates MOR in a concentration-dependent manner (EC50 > 23 μM) .
Cat. No.: HY-R01782A
hsa-miR-5700 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
Cat. No.: HY-165000
CAS No.: 2752265-46-4
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3,4-Difluoro isopropyl U-47700 is a utopioid.
Cat. No.: HY-165021
CAS No.: 2741276-45-7
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3,4-Difluoro propyl U-47700 is a utopioid.
Cat. No.: HY-158967
CAS No.: 2740551-86-2
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3,4-Difluoro-N-desmethyl U-47700 hydrochloride is a utopioid.
Cat. No.: HY-W725197
CAS No.: 2751977-98-5
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3,4-Difluoro-N,N-didesmethyl U-47700 TFA is an opioid.
Cat. No.: HY-172865
Synonyms: 3,4-MDO-U-47700 hydrochloride
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3,4-Methylenedioxy U-47700 (3,4-MDO-U-47700) hydrochloride is a psychoactive substance and a complete agonist of μ-opioid receptor .
Cat. No.: HY-123746
CAS No.: 332132-39-5
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E5700 is an orally active squalene synthase inhibitor, antimalarial agent and antifungal agent with an IC50 of 0.49 nM (without PPi) against squalene synthase from T. cruzi epimastigotes. E5700 shows antiparasitic activities against Trypanosoma cruzi. E5700 inhibits the growth and alters the lipid prolife and the ultrastructure of a multiple agent-resistant C. tropicalis strain. E5700 is a potent and selective inhibitor of the growth of Leishmania amazonensis .
Cat. No.: HY-RI01782
hsa-miR-5700 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
Cat. No.: HY-RI01782A
hsa-miR-5700 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
