2. Gene
  3. HOOK2 - hook microtubule tethering protein 2 Gene

HOOK2 - hook microtubule tethering protein 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as HK2

Gene ID: 29911 | Gene type: protein coding

About HOOK2

Cytogenetic location: 19p13.13 Genomic coordinates (GRCh38): 19:12,763,003-12,792,350 (from NCBI)

This gene has 25 transcripts (splice variants), 192 orthologues and 5 paralogues. Ubiquitous expression in fat (RPKM 18.1), duodenum (RPKM 14.2) and 24 other tissues.

Summary

Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004]

HOOK2 Products(9)

mRNA Protein Name
NM_001100176.2 NP_001093646.1 protein Hook homolog 2 isoform 2
NM_001400041.1 NP_001386970.1 protein Hook homolog 2 isoform 3
NM_001400043.1 NP_001386972.1 protein Hook homolog 2 isoform 4
NM_001400044.1 NP_001386973.1 protein Hook homolog 2 isoform 4
NM_001400045.1 NP_001386974.1 protein Hook homolog 2 isoform 4
NM_001400046.1 NP_001386975.1 protein Hook homolog 2 isoform 4
NM_001400047.1 NP_001386976.1 protein Hook homolog 2 isoform 4
NM_001400048.1 NP_001386977.1 protein Hook homolog 2 isoform 4
NM_013312.3 NP_037444.2 protein Hook homolog 2 isoform 1

HOOK2 Protein Structure

HOOK

HOOK: HOOK protein (1 - 710)

  • 0
  • 200
  • 400
  • 600
  • 719 a.a.
Protein Preferred Names Protein Names

protein Hook homolog 2

h-hook2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06288 HOOK2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus HOOK2 RGD RGD:1310171
Canis familiaris HOOK2 VGNC VGNC:41741
Felis catus HOOK2 VGNC VGNC:62833
Macaca mulatta HOOK2 VGNC VGNC:73425
Mus musculus HOOK2 MGD MGI:2181664
Bos taurus HOOK2 VGNC VGNC:29906