Hacd3 - 3-hydroxyacyl-CoA dehydratase 3 Gene

Also Known as Hcad3; B-ind1; Hspc121; Ptplad1; 4930523M17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 57874

Summary

Predicted to enable 3-hydroxyacyl-CoA dehydratase activity and enzyme binding activity. Acts upstream of or within I-kappaB kinase/NF-kappaB signaling; JNK cascade; and Rho protein signal transduction. Predicted to be located in endoplasmic reticulum and nuclear membrane. Predicted to be integral component of endoplasmic reticulum membrane. Is expressed in several structures, including adrenal gland; central nervous system; gonad; retina; and spleen. Orthologous to human HACD3 (3-hydroxyacyl-CoA dehydratase 3). [provided by Alliance of Genome Resources, Apr 2022]

Hacd3 Products (1)

mRNA Protein Name
NM_021345.2 NP_067320.2 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10747961 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within JNK cascade IDA
IDA: Inferred from direct assay
10747961 MGI
acts upstream of or within Rho protein signal transduction IDA
IDA: Inferred from direct assay
10747961 MGI
involved in negative regulation of intracellular signal transduction IDA
IDA: Inferred from direct assay
10747961 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3

  • butyrate-induced protein 1

  • butyrate-induced transcript 1

  • protein tyrosine phosphatase-like A domain containing 1

  • protein tyrosine phosphatase-like protein PTPLAD1

  • protein-tyrosine phosphatase-like A domain-containing protein 1

  • very-long-chain (3R)-3-

Hacd3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Hacd3 Q8K2C9 PSMD2 Homo sapiens Q13200
Lumier
25036637
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05986 HACD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21591 Hacd3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28109 Hacd3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hacd3 NCBI NCBI:51495