HPSE - Hpse heparanase Gene

Also Known as Hep; Hpa

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64537

Summary

Enables heparanase activity. Predicted to be involved in several processes, including heparan sulfate proteoglycan catabolic process; positive regulation of osteoblast proliferation; and positive regulation of protein kinase B signaling. Predicted to be located in lysosome; membrane raft; and nucleoplasm. Predicted to be part of heparanase complex. Predicted to be active in extracellular matrix and extracellular space. Orthologous to human HPSE (heparanase). [provided by Alliance of Genome Resources, Apr 2022]

HPSE Products (1)

mRNA Protein Name
NM_022605.1 NP_072127.1 heparanase precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables heparanase activity IDA
IDA: Inferred from direct assay
12077130 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heparanase

  • endo-glucoronidase

Recombinant HPSE Proteins

Cat. No. Product Name Accession Purity
HY-P72235 HPSE Protein, Rat (His-Myc) Q71RP1 (K29-E102) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-155410 HPSE1-IN-1 / Unkown
HY-155411 HPSE1-IN-2 / Unkown
HY-182712 HPSE-IN-2 Inhibitor / Unkown
HY-RS06350 HPSE Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06351 HPSE2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W342853 HPSE-IN-1 / Unkown
HY-RS17957 Hpse Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24428 Hpse Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens HPSE NCBI NCBI:10855