Zmynd11 - zinc finger, MYND domain containing 11 Gene
Also Known as BS69; 2210402G22Rik
Species: Mus musculus
Summary
Enables methylated histone binding activity; transcription corepressor activity; and zinc ion binding activity. Involved in regulation of transcription elongation from RNA polymerase II promoter. Predicted to be located in nucleoplasm. Is expressed in early conceptus; inner cell mass; limb mesenchyme; and oocyte. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 30. Orthologous to human ZMYND11 (zinc finger MYND-type containing 11). [provided by Alliance of Genome Resources, Apr 2022]
Zmynd11 Products (12)
| mRNA | Protein | Name |
|---|---|---|
| NM_001199141.2 | NP_001186070.1 | zinc finger MYND domain-containing protein 11 isoform gamma |
| NM_001347470.1 | NP_001334399.1 | zinc finger MYND domain-containing protein 11 isoform beta |
| NM_001347471.1 | NP_001334400.1 | zinc finger MYND domain-containing protein 11 isoform beta |
| NM_001347472.1 | NP_001334401.1 | zinc finger MYND domain-containing protein 11 isoform alpha |
| NM_001347473.1 | NP_001334402.1 | zinc finger MYND domain-containing protein 11 isoform alpha |
| NM_001347474.1 | NP_001334403.1 | zinc finger MYND domain-containing protein 11 isoform gamma |
| NM_001347476.1 | NP_001334405.1 | zinc finger MYND domain-containing protein 11 isoform gamma |
| NM_001347477.1 | NP_001334406.1 | zinc finger MYND domain-containing protein 11 isoform delta |
| NM_001347479.1 | NP_001334408.1 | zinc finger MYND domain-containing protein 11 isoform epsilon |
| NM_001347480.1 | NP_001334409.1 | zinc finger MYND domain-containing protein 11 isoform epsilon |
| NM_001347481.1 | NP_001334410.1 | zinc finger MYND domain-containing protein 11 isoform zeta |
| NM_144516.4 | NP_653099.2 | zinc finger MYND domain-containing protein 11 isoform alpha |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables histone binding |
IPI
IPI: Inferred from physical interaction
|
24590075 | MGI |
| enables methylated histone binding |
IDA
IDA: Inferred from direct assay
|
24590075 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
24590075 | MGI |
| enables transcription corepressor activity |
IMP
IMP: Inferred from mutant phenotype
|
24590075 | MGI |
| enables zinc ion binding |
IDA
IDA: Inferred from direct assay
|
24590075 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in regulation of transcription elongation by RNA polymerase II |
IMP
IMP: Inferred from mutant phenotype
|
24590075 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
zinc finger MYND domain-containing protein 11 |
|
Zmynd11 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Cross
|
Zmynd11 | Q8R5C8 | H3-3A | Homo sapiens | P84243 | 24590075 | |
|
Cross
|
Zmynd11 | Q8R5C8 | H3-3A | Homo sapiens | P84243 | 24590075 | |
|
Cross
|
Zmynd11 | Q8R5C8 | H3-3A | Homo sapiens | P84243 | 24590075 | |
|
Cross
|
Zmynd11 | Q8R5C8 | H3-3A | Homo sapiens | P84243 | 24590075 | |
|
Cross
|
Zmynd11 | Q8R5C8 | H3C1 | Homo sapiens | P68431 | 24590075 | |
|
Cross
|
Zmynd11 | Q8R5C8 | H3C1 | Homo sapiens | P68431 | 24590075 | |
|
Cross
|
Zmynd11 | Q8R5C8 | H3C1 | Homo sapiens | P68431 | 24590075 | |
|
Cross
|
Zmynd11 | Q8R5C8 | H3C1 | Homo sapiens | P68431 | 24590075 |