Nsmce3 - NSE3 homolog, SMC5-SMC6 complex component Gene

Also Known as HCA4; Ndnl2; Mageg1; mage-g1; 5730494G16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66647

Summary

Predicted to enable protein dimerization activity. Acts upstream of or within regulation of DNA-templated transcription. Predicted to be located in chromosome, telomeric region and cytoplasm. Predicted to be part of Smc5-Smc6 complex. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; cerebral cortex; embryo mesenchyme; genitourinary system; and musculature. Orthologous to human NSMCE3 (NSE3 component of SMC5/6 complex). [provided by Alliance of Genome Resources, Jun 2026]

Nsmce3 Products (1)

mRNA Protein Name
NM_023239.5 NP_075728.1 non-structural maintenance of chromosomes element 3 homolog

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
14593116 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
14593116 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Nsmce3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Nsmce3 Q9CPR8 E2f1 Mus musculus Q61501
Anti Bait CoIP
14593116
Intra
Nsmce3 Q9CPR8 E2f1 Mus musculus Q61501
Anti Tag CoIP
14593116
Cross
Nsmce3 Q9CPR8 NGFR Homo sapiens P08138
Anti Tag CoIP
14593116
Cross
Nsmce3 Q9CPR8 NGFR Homo sapiens P08138
Pull Down
14593116
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09597 NSMCE1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09598 NSMCE2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown