SRP9 - signal recognition particle 9 Gene

Also Known as ALURBP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 6726

About SRP9

Cytogenetic location: 1q42.12 Genomic coordinates (GRCh38): 1:225,777,826-225,790,464 (from NCBI)

This gene has 9 transcripts (splice variants) and 212 orthologues. Ubiquitous expression in adrenal (RPKM 131.7), brain (RPKM 102.1) and 25 other tissues.

Summary

Predicted to enable RNA binding activity and signal recognition particle binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be located in cytosol. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. [provided by Alliance of Genome Resources, Apr 2022]

SRP9 Products (2)

mRNA Protein Name
NM_001130440.2 NP_001123912.1 signal recognition particle 9 kDa protein isoform 1
NM_003133.6 NP_003124.1 signal recognition particle 9 kDa protein isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11089964 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SRP9 Protein Structure

SRP9-21

SRP9-21: Signal recognition particle 9 kDa protein (SRP9) (4 - 73)

  • 0
  • 86 a.a.
Protein Preferred Names Protein Names

signal recognition particle 9 kDa protein

  • signal recognition particle 9kD

SRP9 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SRP9 P49458 DPP9 Homo sapiens Q86TI2-2
Validated Y2H
32814053
Intra
SRP9 P49458 DPP9 Homo sapiens Q86TI2-2
Y2H Array
32814053
Intra
SRP9 P49458 DPP9 Homo sapiens Q86TI2-2
Y2H Pooling
32814053
Intra
SRP9 P49458 SRP14 Homo sapiens P37108
Crosslink
30021884
Intra
SRP9 P49458 SRP14 Homo sapiens P37108
Y2H Prey Pooling
32296183
Intra
SRP9 P49458 SRP14 Homo sapiens P37108
Anti Tag CoIP
33961781
Intra
SRP9 P49458 SRP14 Homo sapiens P37108
Anti Tag CoIP
28514442
Intra
SRP9 P49458 SRP14 Homo sapiens P37108
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13776 SRP9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SRP9 VGNC VGNC:35288
Rattus norvegicus SRP9 RGD RGD:1597343
Felis catus SRP9 VGNC VGNC:65686
Mus musculus SRP9 MGD MGI:1350930
Macaca mulatta SRP9 VGNC VGNC:77884
Canis familiaris SRP9 VGNC VGNC:46810
Others SRP9 NCBI