Rnls - renalase, FAD-dependent amine oxidase Gene

Also Known as C10orf59; 6530404N21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67795

Summary

Predicted to enable oxidoreductase activity, acting on NAD(P)H. Predicted to be active in extracellular region. Human ortholog(s) of this gene implicated in essential hypertension and hypertension. Orthologous to human RNLS (renalase, FAD dependent amine oxidase). [provided by Alliance of Genome Resources, Apr 2022]

Rnls Products (1)

mRNA Protein Name
NM_001368833.1 NP_001355762.1 renalase precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables oxidoreductase activity IDA
IDA: Inferred from direct assay
21178975 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cardiac left ventricle morphogenesis IMP
IMP: Inferred from mutant phenotype
21178975 MGI
acts upstream of or within dopamine metabolic process IMP
IMP: Inferred from mutant phenotype
21178975 MGI
acts upstream of or within epinephrine metabolic process IMP
IMP: Inferred from mutant phenotype
21178975 MGI
acts upstream of or within heart contraction IMP
IMP: Inferred from mutant phenotype
21178975 MGI
acts upstream of or within norepinephrine metabolic process IMP
IMP: Inferred from mutant phenotype
21178975 MGI
acts upstream of or within phosphate ion homeostasis IMP
IMP: Inferred from mutant phenotype
23863468 MGI
acts upstream of or within regulation of systemic arterial blood pressure IMP
IMP: Inferred from mutant phenotype
21178975 MGI
acts upstream of or within response to norepinephrine IMP
IMP: Inferred from mutant phenotype
21178975 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

renalase

  • MAO-C

  • alpha-NAD(P)H oxidase/anomerase

  • monoamine oxidase-C

Recombinant Rnls Proteins

Cat. No. Product Name Accession Purity
HY-P71521 Rnls Protein, Mouse (His-SUMO) A7RDN6-1 (A18-I342) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12101 RNLS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18635 Rnls Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25120 Rnls Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rnls NCBI NCBI:55328